EG240549 Activators
Gm4952, a predicted gene with hypothesized glycine N-acyltransferase and glycine N-benzoyltransferase activities, holds a pivotal role in glycine metabolic processes within the mitochondrion. This gene's significance is underscored by its localization, emphasizing its involvement in critical cellular functions related to energy metabolism. Activation of Gm4952 involves a complex interplay of various chemicals. Acetyl-CoA, a crucial metabolite, directly activates Gm4952 by providing acetyl groups for enzymatic activities. Succinyl-CoA and Malonyl-CoA act indirectly by influencing the tricarboxylic acid (TCA) cycle and modulating mitochondrial function, respectively. Alpha-Ketoglutarate, NAD+, Coenzyme A, and AMP play roles in enhancing mitochondrial function and directly or indirectly triggering Gm4952. Citrate, Pyruvate, Oxaloacetate, and Fumarate act as indirect activators by influencing the TCA cycle. Lastly, ATP, a key energy currency, directly activates Gm4952 through phosphorylation reactions.
In summary, Gm4952's activation is intricately tied to the regulation of glycine metabolic processes within the mitochondrion. The direct and indirect activators mentioned contribute to the fine-tuned orchestration of cellular energy metabolism, highlighting Gm4952's crucial role in maintaining mitochondrial function and supporting glycine-related processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $47.00 $92.00 $5826.00 | 3 | |
Acetyl-CoA, a crucial metabolite, directly activates Gm4952 by providing acetyl groups for glycine N-acyltransferase and N-benzoyltransferase activities. Its role in energy metabolism within the mitochondrion supports Gm4952 function, up-regulating glycine metabolic processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Malonyl-CoA, a substrate for fatty acid synthesis, indirectly activates Gm4952 by modulating mitochondrial function. Its impact on cellular energy balance indirectly promotes Gm4952, stimulating glycine metabolic processes within the mitochondrion. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $33.00 $43.00 $63.00 $110.00 $188.00 $738.00 $2091.00 | 2 | |
Alpha-Ketoglutarate serves as an indirect activator by influencing the TCA cycle. Its role in energy metabolism enhances mitochondrial function, indirectly amplifying Gm4952 activity and promoting glycine metabolic processes within the mitochondrion. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ acts as a cofactor, directly activating Gm4952 by supporting enzymatic activities. Its involvement in redox reactions enhances mitochondrial function, triggering Gm4952 and promoting glycine metabolic processes within the mitochondrion. | ||||||
Coenzyme A | 85-61-0 anhydrous | sc-211123 sc-211123A sc-211123B sc-211123C | 10 mg 25 mg 100 mg 250 mg | $83.00 $135.00 $418.00 $801.00 | 1 | |
Coenzyme A, a critical cofactor, directly activates Gm4952 by participating in acyltransferase reactions. Its role in energy metabolism enhances mitochondrial function, directly promoting Gm4952 and stimulating glycine metabolic processes within the mitochondrion. | ||||||
Adenosine phosphate(Vitamin B8) | 61-19-8 | sc-278678 sc-278678A | 50 g 100 g | $160.00 $240.00 | ||
Adenosine phosphate (Vitamin B8) acts as a direct activator of Gm4952 by modulating cellular energy status. Its role in AMP-activated protein kinase (AMPK) signaling enhances mitochondrial function, triggering Gm4952 and promoting glycine metabolic processes within the mitochondrion. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $50.00 $110.00 $145.00 $248.00 $598.00 | 1 | |
Citrate serves as an indirect activator by influencing the TCA cycle. Its role in energy metabolism enhances mitochondrial function, indirectly amplifying Gm4952 activity and promoting glycine metabolic processes within the mitochondrion. | ||||||
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $41.00 $96.00 | ||
Pyruvate, a key metabolite, directly activates Gm4952 by providing substrate for metabolic pathways. Its role in energy metabolism enhances mitochondrial function, directly promoting Gm4952 and stimulating glycine metabolic processes within the mitochondrion. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $306.00 $963.00 $7980.00 | 1 | |
Oxaloacetate serves as an indirect activator by influencing the TCA cycle. Its role in energy metabolism enhances mitochondrial function, indirectly amplifying Gm4952 activity and promoting glycine metabolic processes within the mitochondrion. | ||||||
Diethyl fumarate | 623-91-6 | sc-239732 | 1 L | $146.00 | ||
Diethyl fumarate serves as an indirect activator by influencing the TCA cycle. Its role in energy metabolism enhances mitochondrial function, indirectly amplifying Gm4952 activity and promoting glycine metabolic processes within the mitochondrion. | ||||||