Dynamin II Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore is a small molecule inhibitor that binds to the GTPase domain of dynamin II, preventing its GTPase activity and inhibiting clathrin-mediated endocytosis. | ||||||
Hydroxy-Dynasore | 1256493-34-1 | sc-364678 | 10 mg | $255.00 | ||
Dyngo 4a is a selective inhibitor of dynamin II GTPase activity, interfering with endocytosis and vesicle trafficking processes. | ||||||
Dynamin Inhibitor II | 1119-97-7 | sc-203931 sc-203931A sc-203931B sc-203931C | 5 g 250 g 500 g 1 kg | $47.00 $84.00 $124.00 $198.00 | ||
MiTMAB inhibits dynamin by binding to its pleckstrin homology domain, blocking its interactions with phospholipids and preventing vesicle scission in endocytosis. | ||||||
Dynole 34-2 | 1128165-88-7 | sc-362731 sc-362731A | 10 mg 50 mg | $205.00 $849.00 | ||
Dynole 34-2 is a dynamin inhibitor that interferes with its GTPase activity, disrupting the process of membrane fission during endocytosis and vesicle trafficking. | ||||||
Phthaladyn-23 | 404592-95-6 | sc-364677 | 10 mg | $156.00 | ||
Phthaladyn-23 serves as a selective inhibitor of Dynamin II, exhibiting unique binding affinity that disrupts its conformational changes during endocytosis. This compound alters the GTP hydrolysis rate, leading to a significant delay in the dynamin-mediated membrane fission process. Its distinct molecular interactions enhance the stability of Dynamin II oligomers, thereby modulating the efficiency of vesicle trafficking. The compound's unique structural features facilitate targeted engagement with Dynamin II, differentiating it from other GTPase interactions. | ||||||
Trimethyloctadecylammonium bromide | 1120-02-1 | sc-255699 sc-255699A sc-255699B | 10 g 100 g 1 kg | $75.00 $280.00 $1800.00 | ||
Trimethyloctadecylammonium bromide acts as a modulator of Dynamin II, influencing its oligomerization and membrane interaction dynamics. This compound enhances lipid bilayer stability, promoting unique electrostatic interactions that facilitate membrane curvature. Its long hydrophobic tail contributes to increased membrane fluidity, while the quaternary ammonium group enhances binding affinity to phospholipid surfaces. This dual action alters the kinetics of vesicle scission, impacting cellular trafficking pathways. | ||||||
Mdivi-1 | 338967-87-6 | sc-215291 sc-215291B sc-215291A sc-215291C | 5 mg 10 mg 25 mg 50 mg | $67.00 $126.00 $251.00 $465.00 | 13 | |
Mdivi-1 is known to inhibit dynamin-related protein 1 (Drp1), which has a similar function to dynamin II in mitochondrial fission processes. | ||||||
Pitstop 2 | 1419320-73-2 | sc-507418 | 10 mg | $360.00 | ||
Pitstop 2 is a dynamin inhibitor that targets its GTPase domain, preventing its interactions with clathrin and inhibiting clathrin-mediated endocytosis. | ||||||