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Dynamin Inhibitor II is a cell-permeable cationic surfactant that reversibly inhibits Dynamin I GTPase activity (IC50 = 3.15 muM) by targeting the PH domain and interfering with phospholipid binding. Dynamin Inhibitor II may act to block Dynamin I-dependent SVE (synaptic vesicle endocytosis) in rat brain synaptosomes and Dynamin II-dependent RME (receptor-mediated endocytosis) in non-neuronal HeLa, A431, and COS-7 cells. Inhibition is competitive with respect to PS and noncompetitive with respect to GTP. Dynamin Inhibitor II is an inhibitor of Dynamin II.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dynamin Inhibitor II, 25 g | sc-203931 | 25 g | $47.00 | |||
| US: (Out of Stock: Availability April 3, 2026) | ||||||
Dynamin Inhibitor II, 250 g | sc-203931A | 250 g | $84.00 | |||
Dynamin Inhibitor II, 500 g | sc-203931B | 500 g | $124.00 | |||
Dynamin Inhibitor II, 1 kg | sc-203931C | 1 kg | $198.00 | |||