Date published: 2026-1-12

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DRD1a Activators

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SCH 23390

125941-87-9sc-200408
sc-200408A
5 mg
25 mg
$179.00
$733.00
2
(1)

SCH-23390 is a potent and selective antagonist for the DRD1a receptor, which inhibits dopamine binding and receptor signaling, thus inhibiting DRD1a function.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$77.00
$216.00
18
(1)

Rolipram inhibits phosphodiesterase-4, which increases cAMP levels, potentially affecting the cAMP-responsive elements that regulate DRD1a expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate is a histone deacetylase inhibitor that may increase the acetylation of histones, affecting the transcription of various genes, possibly including DRD1a.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid is another histone deacetylase inhibitor that can lead to changes in gene expression through epigenetic modifications.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine, as an adenosine receptor antagonist, indirectly influences dopaminergic signaling and could alter the expression of dopamine receptors.

Clozapine

5786-21-0sc-200402
sc-200402A
sc-200402B
sc-200402C
50 mg
500 mg
5 g
10 g
$69.00
$364.00
$2500.00
$4100.00
11
(1)

Clozapine is an atypical antipsychotic that, while having a higher affinity for D4 receptors, can antagonize DRD1a receptors as well, reducing their activity.

Haloperidol

52-86-8sc-507512
5 g
$190.00
(0)

Haloperidol, a dopamine receptor antagonist, might induce upregulation of dopamine receptors, including DRD1a, as a compensatory mechanism.

Levodopa

59-92-7sc-205372
sc-205372A
5 g
25 g
$54.00
$171.00
9
(1)

L-DOPA is a precursor to dopamine and might affect dopamine receptor expression due to increased dopamine synthesis.

Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3)

6217-54-5sc-200768
sc-200768A
sc-200768B
sc-200768C
sc-200768D
100 mg
1 g
10 g
50 g
100 g
$94.00
$210.00
$1779.00
$8021.00
$16657.00
11
(1)

Omega-3 fatty acids can influence membrane fluidity and signal transduction pathways, potentially affecting receptor expression.

Tetrabenazine

58-46-8sc-204338
sc-204338A
10 mg
50 mg
$168.00
$721.00
(1)

Tetrabenazine depletes dopamine stores by inhibiting vesicular monoamine transporter 2 (VMAT2), which indirectly leads to the reduced stimulation of DRD1a due to lower synaptic dopamine levels.