DNA Ligase I Antibodies

Santa Cruz Biotechnology provides a broad selection of DNA Ligase I monoclonal antibodies for investigating DNA replication and repair processes. DNA Ligase I monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA Ligase I plays a fundamental role in joining Okazaki fragments during DNA replication and participates in the repair of single-strand breaks in DNA. Proper DNA Ligase I function maintains genomic stability, while its dysregulation has been linked to various diseases, including cancer. Research focused on DNA Ligase I activity and regulation continues to reveal new insights into cellular processes and potential therapeutic targets. Understanding DNA Ligase I mechanisms has advanced knowledge in DNA metabolism and repair pathways. DNA Ligase I research has contributed significantly to our understanding of cell cycle regulation and genome maintenance. Ongoing studies of DNA Ligase I help identify novel approaches for treating DNA repair-related disorders. Santa Cruz Biotechnology monoclonal antibodies for DNA Ligase I support researchers worldwide in advancing scientific discoveries and developing innovative therapeutic strategies.