Date published: 2025-10-11

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DIO1 Antibodies

Santa Cruz Biotechnology delivers a wide array of DIO1 monoclonal antibodies for advanced research in thyroid hormone metabolism. DIO1 Antibodies are suitable for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DIO1, or deiodinase type 1, plays a crucial role in the conversion of thyroxine (T4) to the more active triiodothyronine (T3), thereby regulating thyroid hormone levels in the body. DIO1 is essential for maintaining metabolic homeostasis and influences various physiological processes, including growth, development, and energy metabolism. Understanding DIO1 function is vital for elucidating the mechanisms underlying thyroid-related disorders and metabolic diseases. Research into DIO1 activity continues to reveal new insights about thyroid hormone regulation and its impact on human health. Investigating DIO1 expression patterns helps scientists better understand cellular responses to hormonal changes. Studying DIO1 localization provides valuable information about tissue-specific hormone metabolism. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific knowledge in thyroid hormone regulation and metabolic health.

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DIO1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DIO1 Antibody (B-7)

sc-515198mouse IgG2b κ78-99 (m)WB, IP, IF, ELISAm, r, h
3
(2)

DIO1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DIO1 CRISPR/Cas9 KO Plasmid (h)

sc-405162hGene KnockoutGFP0
(0)

DIO1 HDR Plasmid (h)

sc-405162-HDRhHomology Directed RepairPuromycin0
(0)

DIO1 Double Nickase Plasmid (h)

sc-405162-NIChGene KnockoutPuromycin0
(0)

DIO1 Double Nickase Plasmid (h2)

sc-405162-NIC-2hGene KnockoutPuromycin0
(0)

DIO1 CRISPR/Cas9 KO Plasmid (m)

sc-420002mGene KnockoutGFP0
(0)

DIO1 Double Nickase Plasmid (m)

sc-420002-NICmGene KnockoutPuromycin0
(0)

DIO1 Double Nickase Plasmid (m2)

sc-420002-NIC-2mGene KnockoutPuromycin0
(0)

DIO1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DIO1 CRISPR Activation Plasmid (h)

sc-405162-ACThGene ActivationPuro, Blast, Hygro0
(0)

DIO1 CRISPR Activation Plasmid (h2)

sc-405162-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

DIO1 Lentiviral Activation Particles (h)

sc-405162-LAChGene ActivationPuro, Blast, Hygro0
(0)

DIO1 Lentiviral Activation Particles (h2)

sc-405162-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

DIO1 CRISPR Activation Plasmid (m)

sc-420002-ACTmGene ActivationPuro, Blast, Hygro0
(0)

DIO1 CRISPR Activation Plasmid (m2)

sc-420002-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

DIO1 Lentiviral Activation Particles (m)

sc-420002-LACmGene ActivationPuro, Blast, Hygro0
(0)

DIO1 Lentiviral Activation Particles (m2)

sc-420002-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

DIO1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DIO1 siRNA (h)

sc-77146hGene SilencingN/A
1
(0)

DIO1 shRNA Plasmid (h)

sc-77146-SHhGene SilencingPuromycin
1
(0)

DIO1 shRNA (h) Lentiviral Particles

sc-77146-VhGene SilencingPuromycin
1
(0)

DIO1 siRNA (m)

sc-77147mGene SilencingN/A0
(0)

DIO1 shRNA Plasmid (m)

sc-77147-SHmGene SilencingPuromycin0
(0)

DIO1 shRNA (m) Lentiviral Particles

sc-77147-VmGene SilencingPuromycin0
(0)