Anti-DIO1 Antibody (B-7) is a mouse monoclonal IgG2b (kappa light chain) DIO1 antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 78-99 within an internal region of DIO1 of mouse origin
Anti-DIO1 Antibody (B-7) is recommended for detection of DIO1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-DIO1 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
blocking peptide, sc-515198 P
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DIO1 (B-7): sc-515198.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DIO1 Antibody (B-7) is a high quality monoclonal DIO1 antibody (also designated DIO1 antibody) suitable for the detection of the DIO1 protein of mouse, rat and human origin. DIO1 Antibody (B-7) is available as both the non-conjugated anti-DIO1 antibody form, as well as multiple conjugated forms of anti-DIO1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. DIO1 (deiodinase, iodothyronine, type I), also known as TXDI1, ITDI1 or 5DI, is a 249 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the iodothyronine deiodinase family. Expressed as nine alternatively spliced isoforms, DIO1 functions as a thiol-dependent propylthiouracil-sensitive oxidoreductase that converts the prohormone thyroxine (T4) to bioactive 3,3′,5-triiodothyronine (T3), thereby playing a role in thyroid hormone (TH) activation. Human DIO1 shares 88% sequence similarity with its rat counterpart, suggesting a conserved role between species. The gene encoding DIO1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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