DHRS7B Activators
Vitamin A, being a vitamin A derivative, could potentially affect DHRS7B by altering the availability of its substrates for oxidation-reduction reactions. Similarly, 13-cis-Retinoic acid, also related to vitamin A metabolism, might influence gene transcription and thus upregulate the enzyme's expression through retinoic acid receptors. Fenofibrate and pioglitazone, through their activation of PPARα and PPARγ respectively, could lead to an increase in the transcription of genes related to fatty acid and glucose metabolism, which may include the gene encoding DHRS7B. In this way, these compounds could enhance the enzyme's activity by increasing its expression. Nicotinamide, a precursor to NAD+, could enhance DHRS7B's catalytic efficiency by increasing the bioavailability of NAD+, which is a crucial cofactor for the enzyme's activity. By bolstering the amount of this essential cofactor, nicotinamide may indirectly enhance the enzyme's activity.
Resveratrol, a polyphenolic compound, may activate sirtuins, which play roles in regulating cellular functions, including the expression of various enzymes. This activation has the potential to influence DHRS7B indirectly. Sulforaphane may induce the expression of detoxification enzymes through the Nrf2 pathway; this could potentially affect DHRS7B as part of a broader cellular response to oxidative stress. Curcumin, with its ability to modulate various cellular pathways, could alter the regulatory environment for DHRS7B expression. 1,1-Dimethylbiguanide, Hydrochloride, known for its role in activating AMPK, might lead to a cascade of changes in metabolic enzyme regulation, which could extend to DHRS7B and influence its activity within the context of cellular energy balance. Omega-3 fatty acids like EPA and DHA have been shown to interact with PPARs and might influence DHRS7B activity by affecting the transcription of relevant genes. Polydatin, a derivative of resveratrol, and berberine, an alkaloid, might impact DHRS7B by similar mechanisms, either through sirtuin activation or AMPK stimulation, which can lead to alterations in metabolic enzyme activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Vitamin A | 68-26-8 | sc-280187 sc-280187A | 1 g 10 g | $377.00 $2602.00 | ||
Retinol, a vitamin A derivative, is metabolized by dehydrogenases and might influence the activity of DHRS7B by altering the cellular pool of related substrates or co-factors, thereby impacting the enzyme's activity through substrate availability. | ||||||
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $74.00 $118.00 | 8 | |
As a retinoid, isotretinoin affects gene expression and could modulate the activity of enzymes like DHRS7B through nuclear receptor-mediated changes in gene transcription, possibly leading to an increase in DHRS7B expression. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate activates PPARα and could indirectly enhance the expression of dehydrogenase enzymes, including DHRS7B, by modulating the transcription of genes involved in fatty acid metabolism. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
By acting as a PPARγ agonist, pioglitazone can potentially increase the gene expression of certain dehydrogenases, influencing DHRS7B activity through transcriptional regulation. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide, a precursor to NAD+, can influence the activity of NAD+-dependent enzymes like DHRS7B by increasing the availability of the essential co-factor NAD+, thus potentially enhancing the enzyme's activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has been shown to activate sirtuins, which can affect the expression and function of various enzymes, possibly including DHRS7B, through deacetylation of transcription factors or other proteins that regulate enzyme activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane activates the Nrf2 pathway, which can lead to the upregulation of various detoxifying and antioxidant enzymes, possibly increasing DHRS7B expression as part of the cellular adaptive response to oxidative stress. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate transcription factors and signaling pathways that control the regulation of enzymes, potentially enhancing DHRS7B activity by influencing those regulatory mechanisms. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Metformin activates AMPK, which is known to regulate metabolic pathways, potentially affecting the expression or activity of DHRS7B as part of its action to modulate cellular energy balance. | ||||||
Polydatin | 65914-17-2 | sc-203203 | 10 mg | $92.00 | 5 | |
Polydatin, a resveratrol glucoside, can activate sirtuins and modulate Nrf2, potentially influencing DHRS7B activity through these pathways that regulate cellular defense mechanisms. | ||||||