DHRS2 Activators
DHRS2 activators belong to a distinct chemical class that holds significance in the realm of molecular biology and cellular processes. DHRS2, short for dehydrogenase/reductase SDR family member 2, represents a specific enzyme within the larger family of short-chain dehydrogenases/reductases (SDRs). The SDR family encompasses a diverse group of proteins involved in the oxidation and reduction of a wide array of substrates, contributing to various physiological functions. DHRS2, in particular, plays a crucial role in cellular redox homeostasis by catalyzing the NADP(H)-dependent reduction of carbonyl compounds. It acts as an intricate regulator within cellular metabolic pathways, participating in the modulation of key processes such as lipid metabolism and steroid biosynthesis.
The chemical entities classified as DHRS2 activators are characterized by their ability to modulate the enzymatic activity of DHRS2. These activators interact with the enzyme, influencing its catalytic efficiency and potentially impacting downstream cellular events. Understanding the molecular mechanisms underlying DHRS2 activation is essential for unraveling the intricate web of cellular redox signaling and metabolic regulation. Researchers are delving into the structural and biochemical aspects of DHRS2 activators to decipher their mode of action, aiming to elucidate how these compounds might fine-tune cellular processes by engaging with the DHRS2 enzyme. This chemical class holds promise for shedding light on the intricate network of cellular pathways governed by DHRS2 and may pave the way for novel insights into the broader landscape of cellular physiology and biochemistry.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
As a precursor of NADH, its supplementation might boost DHRS2 activity by increasing cellular NADH levels. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
As a precursor to NAD+, it could amplify DHRS2 activity by elevating cellular NADH levels. | ||||||
D(+)Glucose, Anhydrous | 50-99-7 | sc-211203 sc-211203B sc-211203A | 250 g 5 kg 1 kg | $37.00 $194.00 $64.00 | 5 | |
As a primary energy source, glucose availability can escalate the NAD+/NADH ratio and thus might promote DHRS2 activity. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
By inhibiting glycolysis, 2-DG shifts the redox state of the cell and could potentially stimulate DHRS2 activity. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $44.00 $74.00 $130.00 | ||
As a TCA cycle intermediate, succinate can elevate the cellular redox state, potentially enhancing DHRS2 activity. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $300.00 $944.00 $7824.00 | 1 | |
As another intermediate of the TCA cycle, it can potentially raise the redox state of a cell and enhance DHRS2 activity. | ||||||
Rotenone | 83-79-4 | sc-203242 sc-203242A | 1 g 5 g | $89.00 $254.00 | 41 | |
By inhibiting the mitochondrial electron transport chain, it can shift the redox balance of the cell and might stimulate DHRS2 activity. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $54.00 $62.00 $1642.00 $4600.00 | 51 | |
By inhibiting the mitochondrial electron transport chain, it can shift the redox balance of the cell and might stimulate DHRS2 activity. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Known to modify metabolic pathways, berberine could potentially elevate DHRS2 activity by altering the redox state of the cell or increasing NADH levels. | ||||||