Date published: 2025-10-17

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 51 to 60 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tetrabutylammonium Fluoride Hydrate

22206-57-1sc-251153
sc-251153A
sc-251153B
25 g
500 g
1 kg
$72.00
$238.00
$476.00
(0)

Tetrabutylammonium Fluoride Hydrate acts as a potent derivatization agent, characterized by its ability to facilitate nucleophilic substitution reactions. The quaternary ammonium structure enhances solubility in organic solvents, promoting efficient interaction with various substrates. Its fluoride ion exhibits strong reactivity, enabling the formation of stable covalent bonds. This compound's unique ionic nature allows for selective modifications, influencing reaction kinetics and enhancing the specificity of derivatization processes.

4-Methoxycarbonylphenyl chloroformate

31140-40-6sc-232836
1 g
$135.00
(0)

4-Methoxycarbonylphenyl chloroformate serves as an effective derivatization agent, notable for its electrophilic carbonyl group that readily engages in acylation reactions. This compound's chloroformate functionality promotes rapid ester formation, enhancing the reactivity of alcohols and amines. Its unique ability to stabilize intermediates through resonance effects allows for controlled reaction pathways, optimizing yields. Additionally, its compatibility with diverse functional groups makes it a versatile tool in synthetic chemistry.

Fluorescamine

38183-12-9sc-218500
sc-218500A
100 mg
250 mg
$110.00
$180.00
1
(0)

Fluorescamine is a highly reactive derivatization agent characterized by its ability to form stable fluorescent derivatives with primary amines. Its unique structure facilitates rapid nucleophilic attack, leading to efficient reaction kinetics. The resulting conjugates exhibit enhanced fluorescence, enabling sensitive detection and quantification. Fluorescamine's selectivity for amines over other functional groups allows for precise targeting in complex mixtures, making it a powerful tool in analytical chemistry.

3-Methyl-2-benzothiazolinone hydrazone hydrochloride monohydrate

38894-11-0sc-252026
sc-252026A
2.5 g
10 g
$71.00
$98.00
(0)

3-Methyl-2-benzothiazolinone hydrazone hydrochloride monohydrate serves as a versatile derivatization agent, particularly effective in forming stable hydrazones with carbonyl compounds. Its unique benzothiazolinone moiety enhances electrophilic reactivity, promoting selective interactions with aldehydes and ketones. The resulting derivatives exhibit distinct spectral properties, facilitating their identification and quantification. This compound's ability to stabilize reaction intermediates contributes to its efficiency in complex analytical applications.

3,5-Dimethoxy-α,α-dimethylbenzyl carbazate

39508-00-4sc-252057
5 g
$105.00
(0)

3,5-Dimethoxy-α,α-dimethylbenzyl carbazate acts as a potent derivatization agent, particularly adept at forming stable carbazones with carbonyl groups. Its unique structure, featuring methoxy substituents, enhances solubility and reactivity, allowing for selective interactions with a range of aldehydes and ketones. The resulting derivatives display distinct chromatographic behavior, aiding in their separation and analysis. Additionally, its kinetic profile supports rapid reaction rates, making it suitable for high-throughput applications.

4,4′-Dimethoxytriphenylmethyl chloride

40615-36-9sc-252213
5 g
$49.00
(0)

4,4'-Dimethoxytriphenylmethyl chloride serves as an effective derivatization agent, particularly in the modification of alcohols and amines. Its triphenylmethyl structure provides steric hindrance, promoting selective reactivity and enhancing the stability of the resulting derivatives. The presence of methoxy groups increases electron density, facilitating nucleophilic attacks. This compound exhibits favorable reaction kinetics, allowing for efficient formation of derivatives that can be easily analyzed through various chromatographic techniques.

2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate

53298-30-9sc-251674
5 g
$160.00
(0)

2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate acts as a versatile derivatization agent, particularly for alcohols and amines. Its nitrophenyl moiety enhances electrophilicity, promoting rapid nucleophilic substitution reactions. The methylsulfonyl group contributes to solubility and stability, facilitating smoother reaction pathways. This compound's unique reactivity profile allows for the formation of derivatives with distinct spectroscopic signatures, aiding in analytical differentiation and characterization.

Fluorescence indicator green

68611-47-2sc-228126
sc-228126A
sc-228126B
sc-228126C
50 g
100 g
500 g
1 kg
$199.00
$245.00
$714.00
$1209.00
(1)

Fluorescence indicator green serves as an effective derivatization agent, particularly for amines and carboxylic acids. Its unique structure features a highly conjugated system that enhances light absorption and emission properties, allowing for sensitive detection. The compound's reactivity is characterized by selective electrophilic attack, leading to stable adduct formation. This specificity enables precise tracking of molecular interactions, making it a powerful tool in analytical chemistry.

Dibromobimane

68654-25-1sc-211300
25 mg
$180.00
2
(0)

Dibromobimane is a versatile derivatization agent known for its ability to form stable adducts with thiols and amines through nucleophilic substitution reactions. Its unique dibromobenzene structure facilitates rapid reaction kinetics, promoting efficient labeling. The compound exhibits strong fluorescence, which is enhanced upon reaction, allowing for sensitive detection of target molecules. This property, combined with its selective reactivity, makes it an essential tool for probing molecular environments in various analytical applications.

1-(Pentafluoropropionyl)imidazole

71735-32-5sc-251470
1 ml
$37.00
(0)

1-(Pentafluoropropionyl)imidazole serves as a powerful derivatization agent, characterized by its ability to react selectively with nucleophiles, particularly amines and alcohols. The presence of multiple fluorine atoms enhances its electrophilicity, facilitating rapid acylation reactions. This compound's unique imidazole ring structure allows for specific molecular interactions, promoting the formation of stable derivatives. Its reactivity profile is particularly advantageous for enhancing the sensitivity of analytical techniques.