Date published: 2025-10-1

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2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate (CAS 53298-30-9)

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CAS Number:
53298-30-9
Purity:
≥98%
Molecular Weight:
289.26
Molecular Formula:
C10H11NO7S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate, referred to as MESNP, is a versatile organic compound with a broad spectrum of applications in scientific research. With its unique properties, 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate serves as a valuable reagent for the synthesis of various compounds across multiple disciplines. 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate has been widely utilized in scientific research for diverse purposes. It has proven instrumental in the synthesis of compounds like polymers, pharmaceuticals, and agrochemicals. Moreover, 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate exhibits catalytic properties, making it useful in organic reactions such as the Diels-Alder reaction. The compound has also demonstrated its significance in the synthesis of peptide-based drugs and vaccines. The precise mechanism of action for 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate is not yet fully elucidated, although it is postulated to function as a nucleophile. By forming a covalent bond with an electrophile, 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate facilitates the creation of novel products. Notably, 2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate exhibits exceptional stability in highly acidic environments while maintaining high polarity, which enhances solubility in polar solvents. Furthermore, it displays high base lability and resists hydrogenation without interfering with catalyst activity.


2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate (CAS 53298-30-9) References

  1. [Hormone-receptor interactions. Syntheses of alpha-melanotropin and of informational sequences thereof with the aid of alcali-labile protecting groups (author's transl)].  |  Eberle, A., et al. 1975. Helv Chim Acta. 58: 2106-29. PMID: 172480
  2. The methylsulfonylethyloxycarbonyl group, a new and versatile amino protective function.  |  Tesser, GI. and Balvert-Geers, IC. 1975. Int J Pept Protein Res. 7: 295-305. PMID: 241727

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(Methylsulfonyl)ethyl 4-nitrophenyl carbonate, 5 g

sc-251674
5 g
$160.00