DENND1B Activators
DENND1B Activators are chemical compounds that are known to enhance the functional activity of the DENND1B protein by influencing the signaling pathways and biological processes it is directly involved in. These compounds do not generally activate or inhibit the protein, but rather, they have a direct impact on the specific pathway or function of the DENND1B protein. Each of these chemical compounds interacts with different pathways and mechanisms to enhance the activation of the DENND1B protein.
These compounds are involved in a variety of cellular processes, including the disruption of the Golgi apparatus and endosomal transport, inhibition of clathrin-mediated endocytosis, and the inhibition of numerous kinases, among other actions. Each of these actions can lead to the enhanced activation of the DENND1B protein, as they are all involved in pathways or cellular processes that DENND1B is associated with. For example, disruption of the Golgi apparatus or endosomal transport can lead to an increase in the activity of DENND1B, as these processes are directly involved with the function of this protein.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole destabilizes microtubules, impacting vesicular transport. DENND1B is involved in endosome to Golgi transport and this disruption could potentially enhance its activation. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D inhibits actin polymerization, affecting cytoskeleton-dependent processes. As DENND1B is involved in vesicular transport, changes in actin dynamics may enhance its activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts Golgi apparatus structure, which could impact the function of DENND1B by shifting the balance of membrane trafficking routes, potentially enhancing its activity. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynasore inhibits dynamin, a GTPase involved in vesicle formation. This could potentially enhance the activation of DENND1B, which is also involved in vesicular transport. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $60.00 $108.00 | 21 | |
Chlorpromazine inhibits clathrin-mediated endocytosis. As DENND1B is involved in endosomal transport, inhibition of this process may enhance its activation. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin disrupts endosome to Golgi transport. This could potentially enhance the activation of DENND1B, which is involved in this process. | ||||||
Pitstop 2 | 1419093-54-1 | sc-507418 | 10 mg | $360.00 | ||
Pitstop 2 inhibits clathrin-mediated endocytosis. As DENND1B is involved in endosomal transport, inhibition of these processes may enhance its activation. | ||||||
Golgicide A | 1005036-73-6 | sc-215103 sc-215103A | 5 mg 25 mg | $187.00 $670.00 | 11 | |
Golgicide A inhibits the Arf1 GTPase, disrupting Golgi structure and function. This could potentially enhance the activation of DENND1B, which is involved in Golgi-related processes. | ||||||
H-89 dihydrochloride | 130964-39-5 | sc-3537 sc-3537A | 1 mg 10 mg | $92.00 $182.00 | 71 | |
H-89 is a protein kinase A (PKA) inhibitor. PKA can phosphorylate and enhance the functionality of many proteins, potentially including DENND1B. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor. By inhibiting various kinases, it could potentially enhance the activation of DENND1B. | ||||||