Deacetylase and Histone Modification
Items 121 to 130 of 134 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
cGKI inhibitor | sc-3042 | 0.5 mg/0.1 ml | $97.00 | |||
cGKI inhibitor functions as a potent deacetylase inhibitor, engaging in specific molecular interactions that disrupt the deacetylation of histones. By stabilizing acetylated lysine residues, it alters the conformational landscape of chromatin, influencing gene expression patterns. The compound exhibits unique reaction kinetics, promoting a prolonged presence of acetylated histones, which can lead to enhanced chromatin relaxation and accessibility, thereby affecting epigenetic regulation. | ||||||
HDAC Inhibitor XXIV | sc-364505 | 10 mg | $225.00 | |||
HDAC Inhibitor XXIV acts as a selective deacetylase inhibitor, targeting histone proteins to modulate their acetylation status. Its unique binding affinity facilitates the formation of stable enzyme-inhibitor complexes, effectively hindering the deacetylation process. This compound exhibits distinctive kinetic properties, allowing for a gradual accumulation of acetylated histones, which can significantly impact chromatin structure and dynamics, thereby influencing cellular processes at the epigenetic level. | ||||||
Ac-Arg-Gly-Lys-MCA | sc-391017 sc-391017A | 1 mg 5 mg | $45.00 $180.00 | |||
Ac-Arg-Gly-Lys-MCA functions as a potent deacetylase inhibitor, specifically interacting with histone proteins to alter their acetylation. Its unique structure promotes strong interactions with the active site of deacetylases, leading to a significant reduction in enzymatic activity. The compound's kinetic profile reveals a slow dissociation rate, allowing for sustained inhibition and prolonged effects on histone modification, ultimately affecting chromatin accessibility and gene expression regulation. | ||||||
2,2,2-Trichloroethyl acetate | 625-24-1 | sc-256253 | 5 ml | $226.00 | ||
2,2,2-Trichloroethyl acetate acts as a selective deacetylase inhibitor, engaging with histone proteins through specific hydrogen bonding and hydrophobic interactions. Its unique trifluoromethyl group enhances lipophilicity, facilitating membrane permeability and targeted action. The compound exhibits a distinctive reaction kinetics profile, characterized by a gradual onset of inhibition, which allows for a nuanced modulation of histone acetylation dynamics, influencing chromatin structure and function. | ||||||
Butyrylhydroxamic acid | 4312-91-8 | sc-364450 sc-364450A | 5 mg 25 mg | $66.00 $284.00 | ||
Butyrylhydroxamic acid functions as a potent deacetylase inhibitor, interacting with histone proteins via a unique chelation mechanism that stabilizes the enzyme-substrate complex. Its hydroxamic acid moiety forms strong hydrogen bonds, enhancing specificity and affinity. The compound's distinct steric properties influence its binding kinetics, allowing for a controlled modulation of histone deacetylation, thereby impacting gene expression and chromatin remodeling processes. | ||||||
4-(3,4-Dimethoxyphenyl)butyric acid | 13575-74-1 | sc-226371 | 5 g | $54.00 | ||
4-(3,4-Dimethoxyphenyl)butyric acid acts as a selective deacetylase inhibitor, engaging in specific interactions with histone proteins through its unique aromatic structure. The methoxy groups enhance electron density, facilitating π-π stacking with histone residues. This compound exhibits a distinctive binding profile, promoting conformational changes in the enzyme that modulate catalytic activity. Its structural features contribute to a nuanced regulation of histone acetylation, influencing chromatin dynamics. | ||||||
Demethoxy Curcumin | 22608-11-3 | sc-391590 | 10 mg | $268.00 | ||
Demethoxy Curcumin functions as a potent deacetylase inhibitor, characterized by its ability to interact with histone proteins via its unique polyphenolic structure. The compound's hydroxyl groups enable hydrogen bonding and hydrophobic interactions, stabilizing its binding to the enzyme's active site. This interaction leads to altered enzyme kinetics, enhancing histone acetylation levels and subsequently affecting gene expression regulation. Its distinct molecular architecture plays a crucial role in modulating chromatin accessibility. | ||||||
Triacetylresveratrol | 42206-94-0 | sc-358583 sc-358583A | 1 g 5 g | $216.00 $772.00 | ||
Triacetylresveratrol acts as a selective deacetylase inhibitor, showcasing a unique ability to modulate histone dynamics through its acetylated phenolic framework. The compound's structural features facilitate specific interactions with deacetylase enzymes, promoting conformational changes that influence substrate affinity. This modulation of enzyme activity alters the acetylation status of histones, thereby impacting chromatin structure and gene transcription processes. Its intricate molecular design underscores its role in epigenetic regulation. | ||||||
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH | 125678-68-4 | sc-222009 | 1 mg | $48.00 | ||
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH functions as a potent deacetylase inhibitor, characterized by its unique peptide sequence that enhances binding affinity to histone deacetylases. This compound's specific amino acid composition allows for targeted interactions, stabilizing enzyme-substrate complexes and influencing catalytic efficiency. By altering the deacetylation process, it plays a crucial role in modulating chromatin accessibility and gene expression, highlighting its significance in epigenetic mechanisms. | ||||||
APHS | 209125-28-0 | sc-200668 sc-200668B | 10 mg 100 mg | $330.00 $2045.00 | ||
APHS serves as a selective deacetylase inhibitor, distinguished by its ability to disrupt histone interactions through specific binding motifs. Its structural conformation facilitates unique hydrogen bonding and hydrophobic interactions with target enzymes, enhancing its inhibitory potency. By modulating the acetylation state of histones, APHS influences chromatin remodeling and transcriptional regulation, thereby impacting cellular signaling pathways and gene regulatory networks. | ||||||