DDX36 Activators
The chemical class DDX36 Activators encompasses a range of compounds that could indirectly modulate the activity of DDX36, a DEAD-box helicase involved in RNA metabolism. These compounds do not interact directly with DDX36 but influence the broader cellular processes and pathways related to RNA synthesis, processing, and modification, in which DDX36 plays a crucial role. Inhibitors of RNA polymerase such as Actinomycin D, α-Amanitin, and DRB could create a cellular environment where the demand for RNA processing and modification is altered, leading to an increased requirement for DDX36 activity. By inhibiting RNA synthesis, these compounds might indirectly enhance the role of DDX36 in managing the existing RNA pool within the cell.
Further, compounds that affect epigenetic regulation and gene expression, such as Sodium Butyrate, Trichostatin A, and 5-Azacytidine, might influence DDX36 by altering the expression of genes involved in RNA processing pathways. This alteration in gene expression could indirectly modulate the demand for DDX36's RNA processing capabilities. Similarly, Forskolin and Rapamycin, known to affect cAMP levels and protein synthesis respectively, might also impact RNA processing activities involving DDX36.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Inhibits RNA polymerase and thus RNA synthesis. This could lead to increased reliance on RNA processing and modification mechanisms, potentially enhancing DDX36 activity. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A potent inhibitor of RNA polymerase II, could indirectly increase the demand for RNA processing mechanisms involving DDX36. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA polymerase II, potentially leading to a compensatory increase in RNA processing activities involving DDX36. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Inhibits the spliceosome, potentially impacting RNA splicing and indirectly affecting DDX36 activity in RNA processing. | ||||||
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $290.00 $5572.00 $10815.00 $25000.00 $65000.00 $2781.00 | 63 | |
Another spliceosome inhibitor, which could indirectly enhance DDX36 activity by altering splicing demands. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor affecting gene expression. It might influence DDX36 by altering the expression of genes involved in RNA processing. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Another histone deacetylase inhibitor, potentially affecting gene expression and subsequently RNA processing, which could influence DDX36 activity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can alter gene expression patterns, potentially influencing DDX36 activity indirectly by modifying the cellular RNA landscape. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which might indirectly affect RNA processing activities involving DDX36. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, known to affect protein synthesis and RNA processing, possibly impacting DDX36 activity. | ||||||