Date published: 2026-4-24

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DAP10 Inhibitors

DAP10 inhibitors comprise a diverse array of compounds strategically designed to influence signaling pathways and cellular processes associated with DAP10 modulation. Among these inhibitors, PP2, a potent Src family kinase inhibitor, plays a crucial role in immune responses by targeting Src kinases. Through this targeted inhibition, PP2 can potentially impact DAP10 indirectly by altering cellular processes related to immune cell activation and function. Similarly, PI-103, a dual PI3K/mTOR inhibitor, operates at the intersection of two critical signaling pathways, affecting cell survival and proliferation. Its modulatory effects on these pathways may lead to indirect modulation of DAP10 levels, influencing cellular processes that depend on PI3K and mTOR signaling. Rapamycin, a well-known mTOR inhibitor, provides another avenue for potential DAP10 modulation. By specifically targeting mTOR, Rapamycin impacts protein synthesis and cell growth, potentially influencing DAP10 levels through alterations in cellular processes dependent on the mTOR pathway, such as cell proliferation and differentiation. In addition to these, SB203580, a p38 MAPK inhibitor, contributes to the diverse array of DAP10 inhibitors. By blocking p38 MAPK, SB203580 modulates signaling pathways involved in inflammation and stress responses, potentially impacting DAP10 levels indirectly. The intricate connection between stress responses, immune-related processes, and DAP10 modulation underscores the complexity of the cellular networks involved. Collectively, these DAP10 inhibitors offer valuable insights into the multifaceted regulatory networks governing immune responses and cellular processes. Their targeted actions on specific signaling cascades highlight the intricate interplay of pathways associated with DAP10 activity. As researchers delve deeper into the molecular mechanisms underlying DAP10 modulation, these compounds serve as indispensable tools for unraveling the complexities of immune responses and cellular dynamics influenced by DAP10 in various physiological contexts.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$94.00
$227.00
30
(1)

PP2 is a Src family kinase inhibitor. By targeting Src kinases, it can influence downstream signaling pathways involved in immune responses, potentially indirectly modulating DAP10 by altering cellular processes related to immune cell activation and function.

PI-103

371935-74-9sc-203193
sc-203193A
1 mg
5 mg
$33.00
$131.00
3
(1)

PI-103 is a dual PI3K/mTOR inhibitor. By inhibiting both PI3K and mTOR, it can modulate signaling cascades associated with cell survival and proliferation, potentially indirectly impacting DAP10 by influencing cellular processes dependent on these pathways.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin is an mTOR inhibitor. By targeting mTOR, it can impact protein synthesis and cell growth, potentially indirectly modulating DAP10 levels through alterations in cellular processes dependent on the mTOR pathway, such as cell proliferation and differentiation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 is a PI3K inhibitor affecting the PI3K/Akt signaling pathway. By inhibiting PI3K, it can modulate downstream signaling cascades, potentially indirectly influencing DAP10 levels through alterations in cellular processes regulated by the PI3K/Akt pathway, such as cell survival and growth.

PP242

1092351-67-1sc-301606A
sc-301606
1 mg
5 mg
$57.00
$172.00
8
(1)

PP242 is an mTOR inhibitor. By specifically targeting mTOR, it can impact protein synthesis and cell growth, potentially indirectly modulating DAP10 levels through alterations in cellular processes dependent on the mTOR pathway, such as cell proliferation and differentiation.

AZD8055

1009298-09-2sc-364424
sc-364424A
10 mg
50 mg
$163.00
$352.00
12
(2)

AZD8055 is a dual mTORC1 and mTORC2 inhibitor. By inhibiting both mTOR complexes, it can modulate signaling cascades associated with cell survival and proliferation, potentially indirectly impacting DAP10 by influencing cellular processes dependent on these pathways.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Wortmannin is a PI3K inhibitor that disrupts the PI3K/Akt signaling pathway. By inhibiting PI3K, it can modulate downstream signaling cascades, potentially indirectly influencing DAP10 levels through alterations in cellular processes regulated by the PI3K/Akt pathway, such as cell survival and growth.

PP 1

172889-26-8sc-203212
sc-203212A
1 mg
5 mg
$86.00
$145.00
6
(1)

PP1 is a Src family kinase inhibitor. By targeting Src kinases, it can influence downstream signaling pathways involved in immune responses, potentially indirectly modulating DAP10 by altering cellular processes related to immune cell activation and function.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

SB203580 is a p38 MAPK inhibitor. By blocking p38 MAPK, it can modulate signaling pathways involved in inflammation and stress responses, potentially indirectly influencing DAP10 levels through alterations in cellular stress responses and immune-related processes.

BMS-536924

468740-43-4sc-507397
5 mg
$285.00
(0)

BMS-536924 is a dual kinase inhibitor targeting IGF-1R and IR. By inhibiting these receptors, it can modulate signaling cascades related to cell growth and survival, potentially indirectly impacting DAP10 by influencing cellular processes dependent on IGF-1R and IR pathways.