D55 Inhibitors
Staurosporine and Genistein are kinase inhibitors that prevent the phosphorylation of proteins, a post-translational modification that often regulates protein activity. Rapamycin and LY294002 specifically target components of the PI3K/AKT/mTOR pathway, a key signaling axis that controls cell growth and survival, and thus could affect proteins regulated by this pathway. Further, PD98059 and SB203580 are selective inhibitors of the MAPK pathways, which are critical for cell proliferation, differentiation, and stress responses.
NF449 disrupts G-protein-coupled receptor signaling, while Cyclopamine antagonizes the Hedgehog pathway, both of which are integral to numerous cellular processes. ZM 447439 impedes the action of Aurora kinases, which are essential for cell division, and could affect proteins associated with the cell cycle. U73122 inhibits phospholipase C, influencing downstream signaling molecules and potentially altering proteins that depend on calcium signaling. Proteasome inhibitor Bortezomib is known to increase the levels of many proteins by preventing their degradation, which could change the abundance and activity of various proteins, including D55. Thapsigargin disrupts calcium stores by inhibiting the SERCA pump, potentially affecting calcium-dependent proteins.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A non-selective protein kinase inhibitor that can block the phosphorylation of proteins, possibly including D55 if it is phosphorylation-dependent. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor, which can affect signaling pathways involving tyrosine-phosphorylated proteins, potentially including D55. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can suppress cell growth and proliferation, potentially affecting proteins like D55 that may be regulated by mTOR pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, possibly affecting the PI3K/AKT signaling pathway and any proteins, such as D55, that are regulated by this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of MAPK/ERK kinase, which can prevent the activation of the ERK pathway and influence proteins involved in this signaling route, like D55. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A selective inhibitor of p38 MAPK that can disrupt p38 signaling and affect proteins that are part of the p38 MAPK pathway, potentially including D55. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $199.00 $460.00 $1479.00 | 1 | |
A potent and selective inhibitor of Gs-alpha protein, which can inhibit G-protein-coupled receptor signaling, potentially affecting D55 if it is part of this pathway. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Targets the Hedgehog signaling pathway, which could impact the activity of proteins like D55 if they are regulated by Hedgehog signaling. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor that can disrupt mitotic processes and could influence proteins like D55 if they are involved in cell cycle regulation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that prevents the degradation of proteins, potentially leading to increased levels of proteins including D55 if it is normally degraded by the proteasome. | ||||||