CysLT2 Receptor Activators
CysLT2 receptor activators belong to a class of chemical compounds designed to modulate the activity of the Cysteinyl leukotriene receptor 2 (CysLT2 receptor). The CysLT2 receptor is a G protein-coupled receptor (GPCR) primarily associated with the immune and inflammatory responses within the body. It is a member of the leukotriene receptor family and is activated by cysteinyl leukotrienes, which are lipid mediators produced during inflammation and immune reactions. The CysLT2 receptor is widely distributed in various tissues and cells, including immune cells, smooth muscle cells, and neuronal cells, indicating its involvement in a range of physiological processes beyond its canonical role in inflammatory responses.
CysLT2 receptor activators interact with the CysLT2 receptor, influencing its signaling pathways and downstream cellular responses. These activators may enhance or inhibit the receptor's activity, leading to diverse effects on cellular functions. The modulation of CysLT2 receptor activity has the potential to impact immune responses, smooth muscle contraction, and neuronal signaling, among other processes. Consequently, researchers are investigating the biological consequences of CysLT2 receptor activation and its potential implications in various contexts, such as inflammation, respiratory disorders, and neuronal regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Montelukast Sodium | 151767-02-1 | sc-202231 sc-202231A sc-202231B | 10 mg 25 mg 250 mg | $51.00 $85.00 $161.00 | 5 | |
Montelukast is a leukotriene receptor antagonist that preferentially binds to CysLT1, but at higher concentrations, it can also affect CysLT2 receptor signaling, leading to altered responses in leukotriene-mediated pathways. | ||||||
ONO 1078 | 103177-37-3 | sc-204148 | 50 mg | $66.00 | ||
Pranlukast is another leukotriene receptor antagonist primarily targeting CysLT1. Like Montelukast, it can modulate CysLT2 receptor activity indirectly through its action on CysLT1. | ||||||
Zafirlukast | 107753-78-6 | sc-204942 sc-204942A | 10 mg 100 mg | $37.00 $174.00 | 1 | |
Zafirlukast, by binding to CysLT1 receptors, can indirectly influence CysLT2 receptor pathways. Its higher affinity for CysLT1 allows it to modulate leukotriene-dependent cellular responses that might involve CysLT2. | ||||||
MG 624 | 77257-42-2 | sc-204082 sc-204082A | 10 mg 50 mg | $156.00 $650.00 | 1 | |
MG-624 indirectly affects CysLT2 receptor activation through its action on neuronal nicotinic acetylcholine receptors, influencing leukotriene pathways. | ||||||
LTB4 (Leukotriene B4) | 71160-24-2 | sc-201043 | 50 µg | $374.00 | 4 | |
Leukotriene B4 (LTB4) is a natural ligand for leukotriene receptors and can influence CysLT2 receptor activity as part of its broader role in leukotriene signaling. | ||||||