CYP2T4 Activators
CYP2T4, a member of the cytochrome P450 family, exhibits predicted functionalities encompassing heme binding and monooxygenase activities. Positioned within the cytoplasm and intracellular membrane-bounded organelles, this enzyme is intricately involved in crucial cellular processes, particularly the epoxygenase P450 pathway and xenobiotic metabolism. Its primary function lies in the enzymatic transformation and detoxification of diverse endogenous and exogenous compounds, contributing significantly to the maintenance of cellular homeostasis.
The activation of CYP2T4 involves a multifaceted interplay of direct and indirect mechanisms. Direct activators engage specific regulatory elements, enhancing the enzyme's heme binding and monooxygenase activities. These interactions directly augment the enzymatic functions of CYP2T4, contributing to the epoxygenase P450 pathway and xenobiotic metabolism. On the other hand, indirect activators influence critical signaling pathways, particularly the Nrf2-ARE pathway, modulating the transcriptional machinery governing CYP2T4 expression. This intricate regulation results in increased expression and elevated enzymatic activities, underscoring the adaptability of CYP2T4 in responding to diverse cellular cues. The dynamic interplay of these direct and indirect mechanisms emphasizes the pivotal role of CYP2T4 in cellular processes and highlights its intricate involvement in metabolic pathways essential for cellular function and resilience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol acts as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin serves as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine acts as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin serves as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein acts as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin serves as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Oleanolic Acid | 508-02-1 | sc-205775 sc-205775A | 100 mg 500 mg | $86.00 $302.00 | 8 | |
Oleanolic Acid acts as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $56.00 $180.00 | 8 | |
Ursolic Acid serves as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic Acid acts as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin serves as a direct activator of CYP2T4, enhancing its heme binding and monooxygenase activities. This direct interaction promotes increased enzymatic activity, contributing to the epoxygenase P450 pathway and xenobiotic metabolism facilitated by CYP2T4. | ||||||