CYP2B10 Inhibitors

CYP2B10 inhibitors encompass a range of chemicals designed to regulate the enzyme activity of the CYP2B10 protein, a member of the cytochrome P450 enzyme family. Many members of this enzyme family are involved in the metabolism of xenobiotics and the synthesis of endogenous compounds. The inhibitors listed, such as Ticlopidine, Ketoconazole, and Chloramphenicol, can impede the activity of CYP2B10 and thereby modulate metabolic processes.

Some compounds like Miconazole and Sulconazole are primarily known for their antifungal properties but have a secondary ability to inhibit various CYP450 isoforms. Others, like Fluoxetine and its metabolite Norfluoxetine have the potential to impede CYP2B10 enzyme activity. Calcium channel blockers like Nifedipine and ThioTEPA showcase the diversity in chemical structure and primary function of these inhibitors, but their shared capacity to affect CYP2B10 activity remains central.