CrxOS Activators
CrxOS, a gene predicted to enable transcription cis-regulatory region binding activity, plays a crucial role in cellular processes, particularly blastocyst hatching. This gene is active in the nucleus and expressed in various tissues such as the central nervous system, early conceptus, and retina. Its predicted involvement in blastocyst hatching positions CrxOS as a key regulator during early embryonic development. The ability of CrxOS to bind to transcription cis-regulatory regions suggests its role in orchestrating the expression of genes critical for proper blastocyst hatching, a pivotal event in embryogenesis. The function of CrxOS in blastocyst hatching underscores its significance in facilitating the transition from pre- to post-implantation stages of embryonic development. Blastocyst hatching involves the release of the developing embryo from the surrounding zona pellucida, allowing it to implant into the uterine lining. CrxOS likely contributes to this process by influencing the expression of genes involved in cellular responses during hatching. Understanding the regulatory role of CrxOS in these early developmental events provides valuable insights into the intricate molecular mechanisms governing embryogenesis.
The activation of CrxOS is a complex process involving various molecular players and signaling pathways. While the exact mechanisms remain to be fully elucidated, it is conceivable that external stimuli and intrinsic cellular cues converge to regulate CrxOS activity. Signaling pathways associated with early embryonic development, such as those mediated by growth factors and morphogens, may influence CrxOS expression and function. Additionally, the modulation of chromatin structure and accessibility to cis-regulatory regions could play a role in fine-tuning CrxOS activity during blastocyst hatching. Further research into the precise regulatory networks governing CrxOS activation will contribute to a comprehensive understanding of its role in embryogenesis and may unveil potential strategies for manipulating early developmental processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, an indirect activator, modulates gene expression, enhancing CrxOS activity in transcriptional cis-regulatory region binding. This compound acts as a signaling pathway regulator, contributing to an upregulated function of CrxOS by promoting its involvement in blastocyst hatching and supporting early conceptus development through gene regulation in the nucleus. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride, an indirect activator, influences Wnt signaling, enhancing CrxOS activity in transcriptional cis-regulatory region binding. This compound stabilizes β-catenin, triggering downstream events that support blastocyst hatching and contribute to the target's involvement in the central nervous system and retina through enhanced transcriptional regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, an indirect activator, inhibits histone deacetylases, positively regulating CrxOS activity in transcriptional cis-regulatory region binding. This compound alters chromatin structure, contributing to an upregulated function of CrxOS by enhancing gene expression patterns. This supports blastocyst hatching and maintains the target's involvement in the central nervous system and retina through transcriptional regulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid, an indirect activator, influences histone deacetylases, positively regulating CrxOS activity in transcriptional cis-regulatory region binding. This compound alters chromatin structure, contributing to an enhanced function of CrxOS by promoting gene expression patterns. This supports blastocyst hatching and maintains the target's involvement in the central nervous system and retina through transcriptional regulation. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
5-Aza-2'-deoxycytidine, an indirect activator, inhibits DNA methyltransferases, positively regulating CrxOS activity in transcriptional cis-regulatory region binding. This compound alters DNA methylation patterns, contributing to an upregulated function of CrxOS by enhancing gene expression. This supports blastocyst hatching and maintains the target's involvement in the central nervous system and retina through transcriptional regulation. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B | 10 g 25 g 100 g | $43.00 $62.00 $141.00 | ||
α-Tocopherol, an indirect activator, influences oxidative stress pathways, enhancing CrxOS activity in transcriptional cis-regulatory region binding. This compound acts as an antioxidant, contributing to an upregulated function of CrxOS by mitigating oxidative damage and supporting gene expression patterns. This sustains blastocyst hatching and maintains the target's involvement in the central nervous system and retina through transcriptional regulation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane directly activates CrxOS, stimulating transcription cis-regulatory region binding. This compound, derived from cruciferous vegetables, supports an upregulated function of CrxOS by directly influencing gene regulation. This enhances blastocyst hatching and contributes to the target's involvement in the central nervous system and retina through transcriptional control. | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyric acid, an indirect activator, influences histone acetylation, positively regulating CrxOS activity in transcriptional cis-regulatory region binding. This compound acts as a signaling pathway regulator, contributing to an upregulated function of CrxOS by promoting chromatin modifications. This supports blastocyst hatching and maintains the target's involvement in the central nervous system and retina through enhanced transcriptional regulation. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
Zebularine, an indirect activator, inhibits DNA methyltransferases, positively regulating CrxOS activity in transcriptional cis-regulatory region binding. This compound alters DNA methylation patterns, contributing to an enhanced function of CrxOS by promoting gene expression. This supports blastocyst hatching and maintains the target's involvement in the central nervous system and retina through transcriptional regulation. | ||||||