Cripto Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
SB431542 is a selective inhibitor of the TGF-β type I receptor (ALK5), which is involved in the Cripto signaling pathway. By blocking ALK5, SB431542 hinders the downstream effects of Cripto-mediated TGF-β signaling, potentially inhibiting Cripto-induced cellular responses. | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $89.00 $275.00 | 9 | |
LY2157299 is another TGF-β receptor type I/II inhibitor that affects the TGF-β pathway. It can indirectly modulate Cripto by disrupting the transduction of TGF-β signals. Through this mechanism, LY2157299 may interfere with Cripto-mediated cellular processes. | ||||||
Cerulenin (synthetic) | 17397-89-6 | sc-200827 sc-200827A sc-200827B | 5 mg 10 mg 50 mg | $161.00 $312.00 $1210.00 | 9 | |
Cerulenin is an inhibitor of fatty acid synthase (FASN). Cripto has been linked to lipid metabolism, and by inhibiting FASN, Cerulenin may disrupt lipid-related pathways, indirectly influencing Cripto signaling and functions. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $265.00 | ||
LY3214996 is a pan-TGF-β receptor inhibitor that can impact Cripto signaling. By targeting multiple TGF-β receptors, including those associated with Cripto pathways, LY3214996 may disrupt the transmission of signals initiated by Cripto, potentially leading to inhibition of Cripto-induced effects. | ||||||
DMH-1 | 1206711-16-1 | sc-361171 sc-361171B sc-361171A sc-361171C | 10 mg 25 mg 50 mg 100 mg | $213.00 $318.00 $632.00 $1047.00 | 2 | |
DMH1 is a selective inhibitor of bone morphogenetic protein (BMP) signaling, which is interconnected with Cripto pathways. By blocking BMP signaling, DMH1 can indirectly affect Cripto-mediated cellular responses, potentially acting as an inhibitor of Cripto. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
GW788388 is a TGF-β type I receptor inhibitor with potential relevance to Cripto signaling. Its inhibition of ALK5, a component of the Cripto pathway, may disrupt downstream effects initiated by Cripto, providing a means to modulate Cripto-mediated cellular functions. | ||||||
Fasudil, Monohydrochloride Salt | 105628-07-7 | sc-203418 sc-203418A sc-203418B sc-203418C sc-203418D sc-203418E sc-203418F | 10 mg 50 mg 250 mg 1 g 2 g 5 g 10 g | $18.00 $33.00 $87.00 $168.00 $253.00 $496.00 $910.00 | 5 | |
Fasudil is a Rho kinase (ROCK) inhibitor, and the Rho/ROCK pathway is implicated in Cripto signaling. By inhibiting ROCK, Fasudil may interfere with Cripto-mediated processes, providing indirect inhibition of Cripto signaling and cellular responses. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A83-01 is a selective inhibitor of ALK5, a TGF-β type I receptor involved in the Cripto signaling pathway. Through ALK5 inhibition, A83-01 can modulate TGF-β signaling, potentially influencing Cripto-mediated effects. | ||||||
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
SB505124 is a selective inhibitor of ALK4, a TGF-β type I receptor involved in Cripto signaling. By blocking ALK4, SB505124 may interfere with Cripto-mediated cellular responses, offering a potential means of inhibiting the effects of Cripto signaling. | ||||||