Date published: 2025-10-15

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CREST Antibodies

Santa Cruz Biotechnology provides a broad selection of CREST Antibodies for advanced research in cell biology. CREST Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CREST, or the anti-Centromere antibody, plays a vital role in studying centromere function and chromosome segregation mechanisms during cell division. Research focusing on CREST has revealed significant implications in autoimmune diseases, particularly systemic sclerosis. The detection and characterization of CREST provides valuable insights into disease mechanisms and potential therapeutic targets. Ongoing studies continue to uncover new aspects of CREST's role in cellular regulation and disease progression. Advanced imaging techniques have enhanced our ability to visualize CREST's interaction with cellular components. Recent discoveries have expanded our understanding of CREST's involvement in chromosome stability and cell cycle regulation. Santa Cruz Biotechnology monoclonal antibodies for CREST research support scientists worldwide in advancing cellular and molecular biology knowledge.

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CREST Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CREST Antibody (D-7)

sc-515827mouse IgG2b κ287-312 (m)WB, IP, IF, IHC(P), ELISAm, r, h
1
(4)

CREST Antibody (G-8)

sc-515871mouse IgG1 κ286-314 (m)WB, IP, IF, ELISAm, r, h

new

(0)

CREST CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREST CRISPR/Cas9 KO Plasmid (h)

sc-403134hGene KnockoutGFP
1
(0)

CREST HDR Plasmid (h)

sc-403134-HDRhHomology Directed RepairPuromycin
1
(0)

CREST Double Nickase Plasmid (h)

sc-403134-NIChGene KnockoutPuromycin
1
(0)

CREST Double Nickase Plasmid (h2)

sc-403134-NIC-2hGene KnockoutPuromycin
1
(0)

CREST CRISPR/Cas9 KO Plasmid (m)

sc-435337mGene KnockoutGFP0
(0)

CREST HDR Plasmid (m)

sc-435337-HDRmHomology Directed RepairPuromycin0
(0)

CREST Double Nickase Plasmid (m)

sc-435337-NICmGene KnockoutPuromycin0
(0)

CREST Double Nickase Plasmid (m2)

sc-435337-NIC-2mGene KnockoutPuromycin0
(0)

CREST CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREST CRISPR Activation Plasmid (h)

sc-403134-ACThGene ActivationPuro, Blast, Hygro
1
(0)

CREST CRISPR Activation Plasmid (h2)

sc-403134-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

CREST Lentiviral Activation Particles (h)

sc-403134-LAChGene ActivationPuro, Blast, Hygro
1
(0)

CREST Lentiviral Activation Particles (h2)

sc-403134-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

CREST CRISPR Activation Plasmid (m)

sc-435337-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CREST CRISPR Activation Plasmid (m2)

sc-435337-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CREST Lentiviral Activation Particles (m)

sc-435337-LACmGene ActivationPuro, Blast, Hygro0
(0)

CREST Lentiviral Activation Particles (m2)

sc-435337-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CREST siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CREST siRNA (h)

sc-60441hGene SilencingN/A0
(0)

CREST shRNA Plasmid (h)

sc-60441-SHhGene SilencingPuromycin0
(0)

CREST shRNA (h) Lentiviral Particles

sc-60441-VhGene SilencingPuromycin0
(0)

CREST siRNA (m)

sc-60442mGene SilencingN/A0
(0)

CREST shRNA Plasmid (m)

sc-60442-SHmGene SilencingPuromycin0
(0)

CREST shRNA (m) Lentiviral Particles

sc-60442-VmGene SilencingPuromycin0
(0)