Date published: 2026-5-13

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Cortactin Inhibitors

Cortactin inhibitors belong to a specific chemical class of compounds meticulously designed to modulate the activity of the Cortactin protein. Cortactin is a critical regulatory protein involved in cytoskeletal dynamics, actin filament organization, and cellular migration processes. These inhibitors are thoughtfully crafted molecules engineered to interact with the Cortactin protein, influencing its normal function. Through these interactions, they might impact various cellular processes associated with actin polymerization, cell motility, and cellular morphology, without directly altering its engagement with actin filaments or its role in coordinating cellular structural changes. The design of Cortactin inhibitors is rooted in a comprehensive understanding of the structural and functional attributes of the Cortactin protein. Typically developed using advanced chemical synthesis methods and informed by insights from structural biology, these inhibitors are characterized by their ability to selectively bind to Cortactin. This selectivity enables precise modulation of cellular pathways that rely on the activity of this specific regulatory protein. Unraveling the intricacies of cellular movement, cytoskeletal organization, and cell shape changes often employ Cortactin inhibitors as valuable tools. The development and utilization of Cortactin inhibitors contribute to advancing our knowledge of the complex interplay between cellular components and cytoskeletal dynamics, offering insights into the fundamental molecular mechanisms that govern cellular motility and contribute to cellular architecture.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

Inhibits cortactin-mediated actin polymerization, affecting cytoskeletal dynamics and cell migration.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$321.00
$1040.00
5
(0)

Impairs cortactin-mediated actin filament assembly, potentially influencing cell motility.

SMIFH2

340316-62-3sc-507273
5 mg
$140.00
(0)

Inhibits cortactin-mediated actin polymerization, affecting cellular processes like migration and invasion.

CK-869

388592-44-7sc-507274
5 mg
$163.00
(0)

Inhibits actin polymerization and cellular functions involving cortactin-mediated cytoskeletal dynamics.

Fasudil, Monohydrochloride Salt

105628-07-7sc-203418
sc-203418A
sc-203418B
sc-203418C
sc-203418D
sc-203418E
sc-203418F
10 mg
50 mg
250 mg
1 g
2 g
5 g
10 g
$18.00
$33.00
$87.00
$168.00
$253.00
$496.00
$910.00
5
(1)

Impairs cortactin-mediated cytoskeletal dynamics, possibly affecting cellular processes like migration.