Date published: 2025-10-16

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COQ3 Inhibitors

COQ3 inhibitors belong to a specific class of chemical compounds that play a crucial role in modulating a key biological process within living organisms. These inhibitors are designed to target the COQ3 enzyme, which is a fundamental component of the coenzyme Q (CoQ) biosynthetic pathway. Coenzyme Q, also known as ubiquinone, is a critical molecule involved in mitochondrial electron transport and energy production in eukaryotic cells. It acts as an essential electron carrier within the mitochondrial respiratory chain, facilitating the production of adenosine triphosphate (ATP), the primary energy currency of cells. The COQ3 enzyme, in particular, plays a vital role in the biosynthesis of CoQ, where it catalyzes a specific step in the pathway. Inhibitors of COQ3 are compounds that interfere with the normal enzymatic activity of COQ3, ultimately leading to a disruption in the CoQ biosynthesis process. This disruption can have profound effects on cellular energy production and redox balance, as CoQ is an integral component of the electron transport chain. COQ3 inhibitors are valuable tools in scientific research, as they allow researchers to investigate the role of CoQ in various cellular processes and understand the consequences of inhibiting CoQ biosynthesis. Additionally, these inhibitors may have potential applications in the development of novel strategies for modulating cellular energy metabolism and redox signaling, which could have implications in various fields of biology and biotechnology.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Atovaquone

95233-18-4sc-217675
10 mg
$265.00
2
(0)

Atovaquone inhibits COQ3 by interfering with the electron transport chain in mitochondria, disrupting the synthesis of ubiquinone (CoQ) and impairing energy production. It is used as an antiparasitic and antimalarial drug.

Myxothiazol

76706-55-3sc-507550
1 mg
$145.00
(0)

Myxothiazol blocks COQ3 by binding to the quinol oxidation site of the mitochondrial respiratory chain, disrupting CoQ synthesis and ATP production. It is a potent respiratory chain inhibitor.

Fenazaquin

120928-09-8sc-255170
100 mg
$178.00
(0)

Fenazaquin disrupts COQ3 function by interfering with the electron transport chain, reducing CoQ levels and impacting mitochondrial energy production. It is used as a miticide in agriculture.

Azoxystrobin

131860-33-8sc-364349A
sc-364349
sc-364349B
sc-364349C
25 mg
100 mg
500 mg
1 g
$50.00
$152.00
$458.00
$848.00
1
(0)

Azoxystrobin inhibits COQ3 by interfering with mitochondrial respiration, reducing CoQ levels, and inhibiting energy production. It is a broad-spectrum fungicide.

Pyraclostrobin

175013-18-0sc-229020
100 mg
$65.00
(0)

Pyraclostrobin targets COQ3, disrupting mitochondrial respiration, inhibiting CoQ synthesis, and impairing energy production. It is used as a fungicide.

Dimethyl malonate

108-59-8sc-239778
sc-239778A
250 ml
1 L
$49.00
$102.00
1
(0)

Dimethyl malonate inhibits COQ3 by disrupting the CoQ biosynthetic pathway, leading to decreased CoQ levels and impaired mitochondrial function. It is a small organic molecule.

Fenhexamid

126833-17-8sc-391482
sc-391482A
sc-391482B
100 mg
500 mg
1 g
$210.00
$370.00
$430.00
(0)

Fenhexamid disrupts COQ3 function by interfering with mitochondrial respiration and CoQ synthesis, impacting energy production. It is used as a fungicide.

Fludioxonil

131341-86-1sc-228124
100 mg
$89.00
(0)

Fludioxonil inhibits COQ3 by interfering with mitochondrial respiration, reducing CoQ levels, and impairing energy production. It is a fungicide.

Tefluthrin

79538-32-2sc-236965
100 mg
$127.00
2
(0)

Tefluthrin targets COQ3, disrupting the electron transport chain, inhibiting CoQ synthesis, and impairing mitochondrial energy production. It is an insecticide.