Molecular structure of Myxothiazol, CAS Number: 76706-55-3
Myxothiazol (CAS 76706-55-3)
Alternate Names:
Myxothiazol A
CAS Number:
76706-55-3
Molecular Weight:
487.68
Molecular Formula:
C25H33N3O3S2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Potent inhibitor of the mitochondrial respiratory chain at cytochrome b-c1.
Myxothiazol (CAS 76706-55-3) References
- The mtaA gene of the myxothiazol biosynthetic gene cluster from Stigmatella aurantiaca DW4/3-1 encodes a phosphopantetheinyl transferase that activates polyketide synthases and polypeptide synthetases. | Gaitatzis, N., et al. 2001. J Biochem. 129: 119-24. PMID: 11134965
- Myxothiazol induces H(2)O(2) production from mitochondrial respiratory chain. | Starkov, AA. and Fiskum, G. 2001. Biochem Biophys Res Commun. 281: 645-50. PMID: 11237706
- Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells. | Lai, B., et al. 2006. Neurobiol Dis. 21: 206-16. PMID: 16081299
- Effect of myxothiazol on Leydig cell steroidogenesis: inhibition of luteinizing hormone-mediated testosterone synthesis but stimulation of basal steroidogenesis. | Midzak, AS., et al. 2007. Endocrinology. 148: 2583-90. PMID: 17332065
- A transposon-based strategy to scale up myxothiazol production in myxobacterial cell factories. | Sandmann, A., et al. 2008. J Biotechnol. 135: 255-61. PMID: 18555551
- Inhibition of chlororespiration by myxothiazol and antimycin A in Chlamydomonas reinhardtii. | Ravenel, J. and Peltier, G. 1991. Photosynth Res. 28: 141-8. PMID: 24414973
- A mouse model of mitochondrial complex III dysfunction induced by myxothiazol. | Davoudi, M., et al. 2014. Biochem Biophys Res Commun. 446: 1079-84. PMID: 24661880
- Impact of antimycin A and myxothiazol on cadmium-induced superoxide, hydrogen peroxide, and nitric oxide generation in barley root tip. | Zelinová, V., et al. 2019. Protoplasma. 256: 1375-1383. PMID: 31079230
- Myxothiazol, a new inhibitor of the cytochrome b-c1 segment of th respiratory chain. | Thierbach, G. and Reichenbach, H. 1981. Biochim Biophys Acta. 638: 282-9. PMID: 6274398
- Mitochondrial and nuclear myxothiazol resistance in Saccharomyces cerevisiae. | Thierbach, G. and Michaelis, G. 1982. Mol Gen Genet. 186: 501-6. PMID: 6752659
Inhibitor of:
1190007I07Rik, 2900010M23Rik, ATP5E, BCS1L, CABC1, COX7a2L, COX8a, COX8b, Cstad, CYB5D1, cytochrome b, cytochrome b561, Cytochrome c, Cytochrome c oxidase (COX), cytochrome c1, ERAL1, ETFDH, FASTKD3, GTPBP3, HRPAP20, Magmas, Mimitin, Mimp, mt-TyrRS, MTRF1, NDH II, NDUFA (NADH:ubiquinone oxidoreductase subunit), NDUFB (NADH:ubiquinone oxidoreductase subunit), NDUFB6, NDUFB7, NDUFS, NDUFS5, OSCP1, PET100, PRELI, QCR10, QP-C, RMND1, SCAF1, SQRDL, TaR-1, Tim17A, TTC19, UCRC, Uqcr, UQCRB, UQCRC1, UQCRC2, UQCRH, UQCRHL, and WDR93.Activator of:
MTFmt, and Rieske FeS.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myxothiazol, 1 mg | sc-507550 | 1 mg | $148.00 |