Citrate synthase Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NADH disodium salt | 606-68-8 | sc-205762 sc-205762A | 500 mg 1 g | $89.00 $127.00 | 3 | |
NADH influences citrate synthase indirectly by participating in the electron transport chain. The reduced form of nicotinamide adenine dinucleotide (NADH) can potentially alter the redox state of the cell, indirectly affecting mitochondrial function and citrate synthase. | ||||||
Succinyl coenzyme A sodium salt | 108347-97-3 | sc-215917 sc-215917A | 5 mg 25 mg | $270.00 $1020.00 | 3 | |
Succinyl CoA can potentially influence citrate synthase indirectly by being an intermediate in the TCA cycle. Alterations in succinyl CoA levels may impact the overall TCA cycle, consequently influencing citrate synthase activity. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR influences AMP-activated protein kinase (AMPK), a regulator of cellular energy homeostasis. By activating AMPK, AICAR can indirectly modulate citrate synthase activity, as AMPK can phosphorylate and affect enzymes involved in energy metabolism. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $300.00 $944.00 $7824.00 | 1 | |
Oxaloacetate is a TCA cycle intermediate that can potentially impact citrate synthase indirectly. It may influence the TCA cycle, altering the availability of precursors and substrates, consequently affecting citrate synthase activity. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
Alpha-ketoglutarate is an intermediate in the TCA cycle. Its availability can indirectly influence citrate synthase by affecting the overall flux of the TCA cycle. Changes in alpha-ketoglutarate levels may consequently modulate citrate synthase activity. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $46.00 $80.00 $5712.00 | 3 | |
Acetyl CoA, as a substrate for citrate synthase, directly participates in its catalytic activity. Changes in acetyl CoA levels can directly impact citrate synthase by altering its substrate availability, subsequently influencing the enzyme's activity in the TCA cycle. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $49.00 $108.00 $142.00 $243.00 $586.00 | 1 | |
Citrate is a direct product of citrate synthase and can potentially exhibit feedback inhibition on the enzyme. Elevated citrate levels may directly influence citrate synthase by negatively regulating its own production through feedback inhibition. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
2-Methoxyestradiol is known to disrupt mitochondrial function. Its impact on mitochondrial dynamics and integrity can potentially affect the TCA cycle, indirectly influencing citrate synthase activity. This compound represents an indirect modulator of citrate synthase. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662 is an AMPK activator. By activating AMPK, A769662 can indirectly modulate citrate synthase activity. AMPK activation can lead to phosphorylation events that influence enzymes involved in energy metabolism, indirectly affecting citrate synthase. | ||||||