CILP Inhibitors
CILP inhibitors, also known as Cartilage Intermediate Layer Protein inhibitors, belong to a class of small molecules that have gained attention in the field of molecular biology and drug discovery. These inhibitors target a specific protein called Cartilage Intermediate Layer Protein (CILP), which plays a crucial role in maintaining the integrity and function of cartilage tissues within the body. Cartilage is a connective tissue found in various parts of the body, including the joints, ears, and nose, and is essential for providing structural support and cushioning in these regions. CILP is primarily expressed in cartilage and is believed to be involved in regulating extracellular matrix composition and cartilage development.
CILP inhibitors are designed to modulate the activity of CILP by binding to it and interfering with its normal function. By doing so, they have the potential to influence various processes related to cartilage biology, such as extracellular matrix turnover, chondrocyte differentiation, and cartilage maintenance. Researchers are interested in understanding the molecular mechanisms underlying CILP inhibition and its impact on cartilage health.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $61.00 $77.00 $128.00 $209.00 | 8 | |
Sulfasalazine can inhibit NF-kB, possibly decreasing CILP activity associated with inflammation. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate acts on the immune system, which may lead to a decrease in CILP activity. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $57.00 | 1 | |
Hydroxychloroquine modulates immune activity, which can indirectly affect CILP levels. | ||||||
Auranofin | 34031-32-8 | sc-202476 sc-202476A sc-202476B | 25 mg 100 mg 2 g | $153.00 $214.00 $4000.00 | 39 | |
Auranofin inhibits certain enzymes, indirectly leading to a potential decrease in CILP expression. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin influences gene expression related to inflammatory processes, affecting CILP indirectly. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
Pioglitazone affects PPAR-gamma, which can have an impact on genes expressing CILP. | ||||||