Chromozym TH Activators
Chromozym TH activators encompass a range of chemical compounds that indirectly augment the functional activity of Chromozym TH through various signaling pathways. Cyclic AMP (cAMP), with its ability to serve as a second messenger, plays a pivotal role in activating protein kinase A (PKA), which may lead to the phosphorylation and activation of Chromozym TH or associated regulatory elements. This activation pathway is further exploited by chemicals like Forskolin, which enhances cAMP levels by directly stimulating adenylyl cyclase, and Isoproterenol, an adrenergic agonist that increases cAMP production through receptor-mediated pathways. Similarly, epinephrine interacts with adrenergic receptors, triggering a cascade that results in PKA activation and potential phosphorylation of Chromozym TH. The influence of caffeine and Rolipram, both inhibitors of phosphodiesterase, results in an accumulation of cAMP, thus sustaining the activation of PKA and its downstream effects on Chromozym TH.
In addition to cAMP-mediated pathways, the functional activity of Chromozym TH is modulated by compounds that alter intracellular calcium levels. Ionomycin and A23187, both calcium ionophores, boost intracellular calcium and have the potential to activate calmodulin-dependent kinase (CaMK), which could in turn enhance Chromozym TH activity. Phorbol 12-myristate 13-acetate (PMA) mimics diacylglycer.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases intracellular cAMP levels, which can lead to activation of PKA. PKA can then phosphorylate specific substrates that enhance the activity of Chromozym TH through downstream signaling. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin functions as a calcium ionophore, increasing intracellular calcium levels, which can activate calcium-dependent kinases that in turn activate Chromozym TH. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC) which can phosphorylate target proteins, potentially enhancing the functional activity of Chromozym TH within its specific signaling pathway. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a beta-adrenergic agonist that can increase cAMP levels, indirectly leading to activation of Chromozym TH through cAMP-dependent protein kinase A (PKA) pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin binds to its receptor and initiates a cascade that activates the PI3K/Akt pathway, which could lead to enhanced activity of Chromozym TH through promoting glucose uptake and glycogen synthesis. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
H2O2 acts as a signaling molecule that can modulate the activity of various protein tyrosine phosphatases, potentially leading to enhanced activity of Chromozym TH through oxidative signaling pathways. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
Glutamate is a neurotransmitter that can activate its receptors, leading to calcium influx and activation of calcium-dependent enzymes, possibly enhancing the activity of Chromozym TH in neurons. | ||||||
Calcium dibutyryladenosine cyclophosphate | 362-74-3 | sc-482205 | 25 mg | $147.00 | ||
db-cAMP is a cAMP analog that can activate PKA, leading to phosphorylation of target proteins and potential enhancement of Chromozym TH activity. | ||||||
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Bradykinin activates its G protein-coupled receptor, leading to an increase in intracellular calcium and activation of PKC, which may enhance the activity of Chromozym TH through downstream signaling events. | ||||||