CES4 Inhibitors refer to a specific class of chemical compounds designed to selectively impede the activity of the CES4 enzyme. CES4 stands for Carboxylesterase 4, a member of the carboxylesterase enzyme family that participates in various metabolic and catalytic processes. The development of inhibitors targeting CES4 is instrumental in scientific investigations, providing researchers with specialized tools to dissect the molecular roles and functions associated with this particular enzyme. As part of the broader carboxylesterase family, CES4 likely plays a role in the hydrolysis of ester-containing compounds, contributing to the regulation of cellular lipid metabolism and xenobiotic detoxification.
The design of CES4 inhibitors involves a thorough exploration of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously crafted for specificity, aiming to selectively bind to critical regions of CES4 and disrupt its normal catalytic activities. By utilizing CES4 inhibitors in experimental settings, scientists can unravel the consequences of enzyme inhibition on cellular metabolic processes, shedding light on the potential substrates and physiological roles governed by CES4. The study of CES4 inhibitors contributes to the broader understanding of carboxylesterases and their diverse functions within cellular metabolism, providing valuable insights into the intricate network of enzymatic activities that regulate various biochemical pathways in organisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D inhibits transcription by binding to DNA, preventing RNA polymerase activity, thus suppressing Zds2p expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide hinders protein synthesis by blocking peptide bond formation, leading to reduced levels of Zds2p. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin incorporates into growing polypeptide chains, causing premature termination, and ultimately decreasing Zds2p production. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits bacterial RNA polymerase, affecting transcription processes and indirectly suppressing Zds2p expression. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin inhibits protein synthesis by blocking peptidyl transferase activity, causing a reduction in Zds2p synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin interferes with mRNA synthesis, impacting transcription and subsequently decreasing Zds2p expression. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, a key enzyme in de novo purine synthesis, affecting Zds2p expression indirectly. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $367.00 $520.00 | 20 | |
Blasticidin S inhibits protein synthesis by causing premature termination during translation, reducing the synthesis of Zds2p. | ||||||