Cell Signaling
Items 271 to 280 of 496 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Formoterol fumarate | 43229-80-7 | sc-203050 sc-203050A sc-203050B sc-203050C sc-203050D | 10 mg 50 mg 100 mg 500 mg 1 g | $143.00 $663.00 $1224.00 $3060.00 $5100.00 | 4 | |
Formoterol fumarate plays a significant role in cell signaling through its ability to activate specific G protein-coupled receptors, leading to the modulation of intracellular cyclic AMP levels. This interaction initiates a cascade of phosphorylation events that influence gene expression and cellular responses. Additionally, its unique structural features allow for selective binding, enhancing receptor affinity and promoting sustained signaling effects, which can impact various cellular processes and pathways. | ||||||
AM-251 | 183232-66-8 | sc-200366A sc-200366 sc-200366B sc-200366C | 5 mg 10 mg 50 mg 100 mg | $72.00 $146.00 $624.00 $864.00 | 4 | |
AM-251 is a selective antagonist of cannabinoid receptors, particularly CB1, influencing cell signaling related to neurotransmitter release and synaptic plasticity. By competitively inhibiting receptor activation, it alters the downstream signaling pathways, impacting intracellular calcium levels and cyclic AMP production. This modulation can lead to changes in neuronal excitability and synaptic transmission, highlighting its role in the intricate balance of endocannabinoid signaling within the nervous system. | ||||||
Enoxacin | 74011-58-8 | sc-205670 sc-205670A | 500 mg 1 g | $40.00 $49.00 | 2 | |
Enoxacin plays a pivotal role in cellular signaling by selectively inhibiting certain kinases, thereby modulating phosphorylation events that are crucial for signal transduction. Its unique ability to disrupt protein-protein interactions influences downstream pathways, particularly those involved in stress responses. Additionally, Enoxacin can alter the dynamics of second messengers, such as cyclic AMP, which further impacts cellular functions like metabolism and growth regulation. | ||||||
Flumazenil (Ro 15-1788) | 78755-81-4 | sc-200161 sc-200161A | 25 mg 100 mg | $110.00 $370.00 | 10 | |
Flumazenil acts as a competitive antagonist at the GABA-A receptor, influencing neurotransmitter signaling by blocking the binding of benzodiazepines. This interaction alters chloride ion flow, affecting neuronal excitability and synaptic transmission. Its rapid kinetics allow for swift modulation of inhibitory signaling pathways, which can lead to changes in cellular responses to stimuli. Additionally, Flumazenil's selectivity for specific receptor subtypes highlights its nuanced role in fine-tuning synaptic activity. | ||||||
Fluconazole | 86386-73-4 | sc-205698 sc-205698A | 500 mg 1 g | $54.00 $84.00 | 14 | |
Fluconazole functions as a potent inhibitor of fungal cell signaling pathways by targeting the enzyme lanosterol 14α-demethylase, crucial for ergosterol biosynthesis. This interaction disrupts membrane integrity and fluidity, leading to altered cellular communication. Its specificity for the cytochrome P450 enzyme system allows for selective modulation of metabolic processes, impacting growth and replication. The compound's affinity for binding sites influences reaction kinetics, resulting in a cascade of downstream effects on cellular homeostasis. | ||||||
Zafirlukast | 107753-78-6 | sc-204942 sc-204942A | 10 mg 100 mg | $37.00 $174.00 | 1 | |
Zafirlukast acts as a selective antagonist of leukotriene receptors, modulating cell signaling pathways involved in inflammatory responses. By binding to these receptors, it inhibits the action of leukotrienes, which are key mediators in various cellular processes. This interaction alters intracellular signaling cascades, affecting gene expression and cytokine release. The compound's unique binding affinity influences receptor conformation, leading to distinct downstream effects on cellular behavior and communication. | ||||||
(+)-Pilocarpine hydrochloride | 54-71-7 | sc-203196 sc-203196A sc-203196B | 1 g 100 g 10 g | $62.00 $3641.00 $520.00 | 3 | |
(+)-Pilocarpine hydrochloride functions as a selective agonist for muscarinic acetylcholine receptors, initiating a cascade of intracellular signaling events. Its binding enhances phospholipase C activity, resulting in increased inositol trisphosphate and diacylglycerol levels. This activation leads to elevated intracellular calcium concentrations, influencing various cellular functions such as secretion and smooth muscle contraction, thereby modulating diverse physiological responses. | ||||||
L-Glutamine | 56-85-9 | sc-391013 sc-391013C sc-391013A sc-391013D sc-391013B | 100 g 250 g 1 kg 5 kg 10 kg | $37.00 $47.00 $99.00 $379.00 $733.00 | 2 | |
L-Glutamine serves as a crucial signaling molecule, influencing cellular metabolism and gene expression. It participates in the mTOR pathway, promoting protein synthesis and cell growth. Additionally, it acts as a nitrogen donor in the synthesis of nucleotides and amino acids, facilitating cellular proliferation. Its role in modulating the immune response is significant, as it regulates the activity of immune cells through metabolic reprogramming, enhancing their function during stress conditions. | ||||||
DAF-FM DA (cell permeable) | 254109-22-3 | sc-205940 | 1 mg | $745.00 | 7 | |
DAF-FM DA is a cell-permeable fluorescent probe that selectively reacts with nitric oxide, facilitating the study of its signaling pathways. Upon interaction with nitric oxide, it undergoes a chemical transformation that enhances its fluorescence, allowing real-time visualization of nitric oxide dynamics in live cells. This unique property enables researchers to investigate the kinetics of nitric oxide production and its role in various cellular processes, including vasodilation and apoptosis. | ||||||
NFκB Activation Inhibitor III | 380623-76-7 | sc-204818 | 5 mg | $115.00 | 3 | |
NFκB Activation Inhibitor III is a selective modulator of the NFκB signaling pathway, known for its ability to disrupt the interaction between IκB proteins and NFκB dimers. By inhibiting this complex formation, it prevents the translocation of NFκB to the nucleus, thereby altering gene expression profiles. This compound exhibits unique kinetics in its binding affinity, influencing downstream inflammatory responses and cellular stress mechanisms, making it a critical tool for dissecting cellular signaling networks. | ||||||