Formoterol fumarate CAS: 43229-80-7
MF: 2C19H24N2O4•C4H4O4
MW: 804.89
A potent β2-AR agonist.

Formoterol fumarate (CAS 43229-80-7)

Formoterol fumarate | CAS 43229-80-7 is rated 5.0 out of 5 by 1.
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Alternate Names: Foradil
Application: Formoterol fumarate is a potent β2-AR agonist
CAS Number: 43229-80-7
Purity: ≥99%
Molecular Weight: 804.89
Molecular Formula: 2C19H24N2O4•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Formoterol Fumarate is shown to be a potent β-AR adrenoceptor agonist, with a fast onset of effect on the isolated human bronchus model. This compound demonstrates a 330-fold selectivity for β2 over β1 receptors. Formoterol Fumarate has been reported to be 150-200 times more potent than isoprenaline. This agent has also been noted to reduce the loss of muscle mass in murine models.


References

1. Decker, N., et al. 1982. J. Pharm. Pharmacol. 34: 107-112. PMID: 6121868
2. Naline, E., et al. 1994. Eur. Respir. J. 7: 914-920. PMID: 7914176
3. Kenley, R.A., et al. 2008. Oncol. Rep. 19: 1113-1121. PMID: 18425366

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water, and DMSO (20 mg/ml).
Storage :
Store at 4° C
Melting Point :
136-142° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9919001
MDL Number :
MFCD11045919
SMILES :
CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O.C(=CC(=O)O)C(=O)O.O.O

Download SDS (MSDS)

Certificate of Analysis

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Formoterol fumarate (CAS 43229-80-7)  Product Citations

See how others have used Formoterol fumarate (CAS 43229-80-7). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 25751092  Salomon, JJ. et al. 2015. Mol. Pharm. 12: 2633-41.

PMID: # 33015009  Front Bioeng Biotechnol. 1030.

PMID: # 32861927  J Pharm Biomed Anal. 113530.

Citations 1 to 3 of 3 total

When the chemical dissolved in DMSO, how long can it be stored? 

Asked by: hawkeye11
Thank you for you question. Formoterol fumarate,sc-203050, can be stored for 6 months at -80℃ once dissolved in DMSO.
Answered by: TechService7
Date published: 2016-12-23
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Rated 5 out of 5 by from Kenley et al Kenley et al. (PubMed ID 18425366) found that formoterol fumarate decreased muscle mass loss in rats with induced cancer cachexia. -SCBT Publication Review
Date published: 2015-04-14
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