(+)-Pilocarpine hydrochloride (CAS 54-71-7)
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(+)-Pilocarpine hydrochloride is a cholinergic agonist that acts as a muscarinic receptor stimulant. It functions by binding to and activating muscarinic acetylcholine receptors, leading to the stimulation of smooth muscle, glandular secretions, and the central nervous system. (+)-Pilocarpine Hydrochloride′s mechanism of action involves increasing the levels of intracellular cyclic guanosine monophosphate (cGMP) and calcium, resulting in the activation of phospholipase C and the subsequent release of inositol trisphosphate and diacylglycerol. This cascade of events ultimately leads to the opening of potassium channels and the depolarization of cell membranes. In experimental applications, (+)-Pilocarpine hydrochloride is used to induce salivation, lacrimation, and sweating, making it useful for studying the physiological effects of muscarinic receptor activation. Its ability to target muscarinic receptors without affecting nicotinic receptors may be a useful chemical for investigating the role of muscarinic signaling pathways in various biological processes.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Pilocarpine hydrochloride, 1 g | sc-203196 | 1 g | $61.00 | |||
(+)-Pilocarpine hydrochloride, 10 g | sc-203196B | 10 g | $510.00 | |||
(+)-Pilocarpine hydrochloride, 100 g | sc-203196A | 100 g | $3570.00 |