CEACAM18 Inhibitors
CEACAM18 inhibitors belong to a specialized class of chemical compounds that target CEACAM18, a specific cell adhesion molecule that plays a crucial role in various cellular processes, particularly in cell-cell interactions and immune regulation. CEACAM18, short for Carcinoembryonic Antigen-Related Cell Adhesion Molecule 18, is a member of the CEACAM family, which encompasses a group of glycoproteins primarily found on the surface of cells, particularly in epithelial tissues and immune cells. These glycoproteins are known for their involvement in mediating cell adhesion, signal transduction, and immune response regulation. CEACAM18, in particular, has been identified as an important player in immune cell signaling and modulation, making it a promising target for pharmaceutical intervention.
CEACAM18 inhibitors are designed to modulate the activity of CEACAM18, either by blocking its binding sites or by interfering with its downstream signaling pathways. By doing so, these inhibitors can potentially influence cell adhesion, immune cell activation, and other cellular functions associated with CEACAM18. The development and study of CEACAM18 inhibitors hold promise for understanding the intricate mechanisms underlying immune responses and cell communication, which may have implications in various fields of biology and medicine.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
EGFR inhibitors like Gefitinib can impact signaling pathways that may be associated with CEACAM18. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
By inhibiting PI3K, this compound could affect downstream signaling relevant to CEACAM18. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibiting mTOR could influence pathways associated with CEACAM18, affecting its function indirectly. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
These inhibitors can affect Src family kinase signaling, potentially modulating CEACAM18-related pathways. | ||||||
Fludarabine | 21679-14-1 | sc-204755 sc-204755A | 5 mg 25 mg | $58.00 $204.00 | 15 | |
By inhibiting STAT, these compounds could modulate signaling pathways related to CEACAM18. | ||||||
Perifosine | 157716-52-4 | sc-364571 sc-364571A | 5 mg 10 mg | $188.00 $327.00 | 1 | |
Targeting AKT signaling, these inhibitors could influence pathways associated with CEACAM18. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
HSP90 inhibitors can modulate protein folding and stability, potentially affecting CEACAM18 indirectly. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
By inhibiting NF-κB, this compound could influence signaling pathways relevant to CEACAM18. | ||||||