Date published: 2026-4-25

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Cdx4 Activators

Cdx4 activators belong to a chemical class of compounds designed to modulate the activity of the Cdx4 transcription factor. Cdx4, short for Caudal-type homeobox transcription factor 4, is a member of the homeobox gene family, known for its critical role in embryonic development and tissue differentiation. Homeobox genes like Cdx4 encode transcription factors that regulate the expression of other genes, thereby influencing various cellular processes during early development.

The role of Cdx4 activators is to interact with the Cdx4 protein and potentially enhance or regulate its transcriptional activity. This modulation can influence the expression of downstream target genes involved in various developmental processes, including the formation of the digestive tract, spinal cord development, and the differentiation of tissues along the anterior-posterior axis. Research into Cdx4 activators contributes to our understanding of the intricate molecular mechanisms that govern embryonic development and tissue patterning. It provides insights into how specific transcription factors like Cdx4 orchestrate the precise genetic programs required for the proper formation and differentiation of tissues and organs in the developing embryo. Further investigation into the precise mechanisms of action and the biological consequences of Cdx4 activation is necessary to deepen our understanding of its role in development and cellular differentiation.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid affects the differentiation of cells and might upregulate Cdx4 expression as part of developmental processes.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methyltransferase inhibitor can change gene expression by affecting DNA methylation status, possibly affecting Cdx4.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

As a modulator of epigenetic marks, it may influence the expression of genes involved in development like Cdx4.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

It acts as a histone deacetylase inhibitor, potentially increasing the expression of genes by affecting chromatin structure.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

It can activate the Wnt signaling pathway and may upregulate genes involved in development like Cdx4.

Dimethyl Sulfoxide (DMSO)

67-68-5sc-202581
sc-202581A
sc-202581B
100 ml
500 ml
4 L
$31.00
$117.00
$918.00
136
(6)

DMSO can influence differentiation and gene expression in various cell types and may affect Cdx4 expression indirectly.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

A synthetic retinoid known to influence embryonic development and gene expression patterns.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

VPA is an HDAC inhibitor that can alter gene expression and has potential effects on the expression of developmental genes like Cdx4.