Cdx4 activators belong to a chemical class of compounds designed to modulate the activity of the Cdx4 transcription factor. Cdx4, short for Caudal-type homeobox transcription factor 4, is a member of the homeobox gene family, known for its critical role in embryonic development and tissue differentiation. Homeobox genes like Cdx4 encode transcription factors that regulate the expression of other genes, thereby influencing various cellular processes during early development.
The role of Cdx4 activators is to interact with the Cdx4 protein and potentially enhance or regulate its transcriptional activity. This modulation can influence the expression of downstream target genes involved in various developmental processes, including the formation of the digestive tract, spinal cord development, and the differentiation of tissues along the anterior-posterior axis. Research into Cdx4 activators contributes to our understanding of the intricate molecular mechanisms that govern embryonic development and tissue patterning. It provides insights into how specific transcription factors like Cdx4 orchestrate the precise genetic programs required for the proper formation and differentiation of tissues and organs in the developing embryo. Further investigation into the precise mechanisms of action and the biological consequences of Cdx4 activation is necessary to deepen our understanding of its role in development and cellular differentiation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid affects the differentiation of cells and might upregulate Cdx4 expression as part of developmental processes. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor can change gene expression by affecting DNA methylation status, possibly affecting Cdx4. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
As a modulator of epigenetic marks, it may influence the expression of genes involved in development like Cdx4. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
It acts as a histone deacetylase inhibitor, potentially increasing the expression of genes by affecting chromatin structure. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
It can activate the Wnt signaling pathway and may upregulate genes involved in development like Cdx4. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $31.00 $117.00 $918.00 | 136 | |
DMSO can influence differentiation and gene expression in various cell types and may affect Cdx4 expression indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A synthetic retinoid known to influence embryonic development and gene expression patterns. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
VPA is an HDAC inhibitor that can alter gene expression and has potential effects on the expression of developmental genes like Cdx4. | ||||||