Cdk5 Inhibitors
Items 21 to 30 of 39 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cdc2-Like Kinase Inhibitor, TG003 | 300801-52-9 | sc-202528 sc-202528A | 5 mg 25 mg | $139.00 $548.00 | 6 | |
TG003 blocks CDK5 activity by binding to the ATP-binding pocket, preventing the enzyme from phosphorylating its substrates. | ||||||
Butyrolactone I | 87414-49-1 | sc-201533 sc-201533A | 200 µg 1 mg | $122.00 $514.00 | 1 | |
Butyrolactone I functions as a CDK5 inhibitor by disrupting the interaction between CDK5 and its activator, p35. | ||||||
Hymenidin | 107019-95-4 | sc-202177 | 1 mg | $263.00 | ||
Hymenidin (CAS 107019-95-4) acts as a Cdk5 inhibitor, influencing vital cellular processes associated with this enzyme. Its inhibitory function in relation to Cdk5 has broad effects on various cellular activities. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 acts as a CDK5 inhibitor by suppressing the kinase activity through competitive inhibition at the ATP-binding site. | ||||||
N9-Isopropyl-olomoucine | 158982-15-1 | sc-202264 sc-202264A | 1 mg 5 mg | $181.00 $650.00 | 1 | |
N9-Isopropyl-olomoucine (CAS 158982-15-1) functions as a Cdk5 inhibitor, modulating essential cellular processes associated with this enzyme. Its inhibitory role in relation to Cdk5 has significant effects on various cellular activities. | ||||||
CR8, (R)-Isomer | 294646-77-8 | sc-311306 | 5 mg | $174.00 | ||
CR8, (R)-Isomer (CAS 294646-77-8) acts as a Cdk5 inhibitor, influencing crucial cellular processes associated with this enzyme. Its inhibitory function in relation to Cdk5 has diverse effects on various cellular activities. | ||||||
Indirubin-3′-monoxime-5-sulphonic Acid | 331467-05-1 | sc-221753 | 1 mg | $187.00 | 1 | |
Indirubin-3'-monoxime-5-sulphonic Acid acts as a Cdk5 modulator through its ability to form hydrogen bonds and hydrophobic interactions with key residues in the enzyme's active site. This compound's structural features promote a conformational shift in Cdk5, which can alter its catalytic efficiency. The sulfonic acid moiety enhances aqueous solubility, allowing for improved accessibility to the enzyme, thereby influencing reaction kinetics and cellular signaling cascades. | ||||||
Cdk4/6 Inhibitor IV | 359886-84-3 | sc-203874 | 5 mg | $265.00 | 3 | |
Cdk4/6 Inhibitor IV exhibits unique interactions with Cdk5 by stabilizing its inactive conformation through specific electrostatic interactions and steric hindrance. This compound's distinct structural motifs facilitate selective binding, effectively modulating the enzyme's activity. Its ability to disrupt critical phosphorylation pathways highlights its role in regulating cellular processes, while its lipophilic characteristics may influence membrane permeability and localization within cellular compartments. | ||||||
Aloisine A | 496864-16-5 | sc-202451 | 1 mg | $62.00 | ||
Aloisine A demonstrates a remarkable ability to selectively inhibit Cdk5 through intricate molecular interactions that involve hydrogen bonding and hydrophobic contacts. This compound alters the enzyme's conformational dynamics, leading to a decrease in its kinase activity. Its unique structural features allow for specific recognition of Cdk5, impacting downstream signaling pathways. Additionally, its solubility properties may affect its distribution and interaction with cellular targets, enhancing its regulatory potential. | ||||||
GSK-3 Inhibitor IX, Control, MeBIO | 710323-61-8 | sc-221688 | 1 mg | $135.00 | ||
GSK-3 Inhibitor IX, Control, MeBIO exhibits a distinctive mechanism of action by modulating the phosphorylation state of substrates through its interaction with Cdk5. This compound engages in specific electrostatic interactions that stabilize the enzyme-substrate complex, influencing reaction kinetics. Its unique steric configuration facilitates selective binding, potentially altering the enzyme's catalytic efficiency. Furthermore, its lipophilic characteristics may enhance membrane permeability, impacting cellular localization and interaction dynamics. | ||||||