CdcA4 Activators
Cell Division Cycle Associated 4 (CDCA4) is a protein-coding gene found in humans. It's believed to play a crucial role in cell cycle progression and regulation. CDCA4 is a member of the E2F family of transcription factors, which are pivotal in controlling the cell cycle and the action of tumor suppressor proteins.CDCA4 is involved in the G1/S transition phase of the cell cycle, where cells prepare for DNA replication. It's expressed in a cell cycle-dependent manner and is maximally induced as cells enter S phase, suggesting a role in the initiation of DNA synthesis.
Recent studies have associated CDCA4 with cancer onset and progression. Abnormal expression levels of CDCA4 have been observed in various human cancers, including lung, breast, and liver cancers, implying that it could serve as a biomarker for these malignancies. Its overexpression is often correlated with poor prognosis, making it a target for anti-cancer strategies.In summary, CDCA4 is a key player in cell cycle regulation, especially during the transition from the G1 to the S phase. Its role in cancer progression is being actively studied, and it may serve as a prognostic marker. However, the exact mechanistic involvement of CDCA4 in these processes requires further investigation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
A potent inhibitor of cyclin-dependent kinases (CDKs) like CDK2, CDK7, and CDK9, which indirectly influences cell cycle regulatory proteins including those associated with CDCA4. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
A selective inhibitor of CDK4 and CDK6, affecting cell cycle progression, potentially altering the function of proteins related to CDCA4. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
A broad-spectrum CDK inhibitor, affecting various cell cycle-related proteins and possibly impacting CDCA4 function indirectly. | ||||||
Olomoucine | 101622-51-9 | sc-3509 sc-3509A | 5 mg 25 mg | $72.00 $274.00 | 12 | |
A selective inhibitor for certain CDKs, which might influence proteins in the CDCA4 regulatory network. | ||||||
Purvalanol B | 212844-54-7 | sc-361300 sc-361300A | 10 mg 50 mg | $199.00 $846.00 | ||
A potent CDK inhibitor, targeting key enzymes in cell cycle regulation, potentially affecting CDCA4-associated pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which plays a role in cell cycle regulation and might indirectly affect CDCA4. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor, involved in cell cycle control, which may have implications for CDCA4 activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor, affecting various signaling pathways, including those related to cell cycle regulation and potentially CDCA4. | ||||||