Date published: 2026-3-9

1-800-457-3801

SCBT Portrait Logo
Seach Input

Cdc50C Inhibitors

Cdc50C Inhibitors encompass a range of chemical compounds that indirectly attenuate the functional activity of Cdc50C through targeted disruption of cellular processes and signaling pathways. Brefeldin A, by impeding ARF-dependent vesicle formation, compromises the Golgi apparatus and trafficking processes essential for Cdc50C function, thus leading to its diminished activity. Similarly, Dynasore hinders dynamin-mediated endocytosis, which can obstruct Cdc50C's proper membrane localization and functionality. ML 141's inhibition of Cdc42 and the resultant disruption in actin cytoskeleton organization can attenuate processes that Cdc50C may be reliant upon, while Monensin's alteration of ion gradients and vesicle acidification would indirectly limit Cdc50C's ion-dependent functions. Nocodazole and CK 666, by disrupting microtubules and inhibiting actin nucleation respectively, could stifle Cdc50C's activity if it is contingent on cytoskeletal integrity for vesicle transport or cell morphology regulation. The inhibition of protein kinase C by Gö 6976, if Cdc50C is regulated through PKC-mediated phosphorylation, could lead to its decreased activity, just as Latrunculin B's prevention of actin polymerization could hinder actin-dependent Cdc50C functions. ZCL278 and NSC 23766, which target Cdc42 and Rac1 respectively, have the potential to diminish Cdc50C activity by altering the GTPase-mediated pathways crucial for vesicle formation and trafficking. The stabilization of actin filaments by Jasplakinolide might paradoxically impede Cdc50C's function by preventing necessary actin turnover, while Y-27632's inhibition of ROCK signaling could similarly reduce Cdc50C's activity by altering actin cytoskeleton dynamics. Collectively, these inhibitors employ diverse mechanisms to reduce the functional activity of Cdc50C, highlighting the intricate network of cellular processes upon which Cdc50C's function is dependent.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Brefeldin A disrupts the Golgi apparatus structure by inhibiting ADP-ribosylation factor (ARF), which is crucial for vesicle formation in the secretory pathway. As Cdc50C is associated with trafficking and transport processes, the disruption of Golgi apparatus function by Brefeldin A likely leads to the diminished functional activity of Cdc50C.

Dynamin Inhibitor I, Dynasore

304448-55-3sc-202592
10 mg
$89.00
44
(2)

Dynasore is a GTPase inhibitor that impairs dynamin-mediated endocytosis. Since Cdc50C may be involved in vesicular transport, inhibiting endocytosis can indirectly decrease the functional activity of Cdc50C by preventing its proper localization to cellular membranes.

ML 141

71203-35-5sc-362768
sc-362768A
5 mg
25 mg
$137.00
$512.00
7
(1)

ML 141 is a selective inhibitor of Cdc42, a small GTPase. By inhibiting Cdc42, which is involved in actin cytoskeleton organization, ML 141 can indirectly lead to diminished functional activity of Cdc50C if Cdc50C's function is linked to cytoskeletal dynamics or cell morphology.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

Monensin is an ionophore that disrupts intracellular ion gradients and affects vesicle acidification. This ion disruption can indirectly diminish the activity of Cdc50C by altering the ion-dependent processes it requires for proper function.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

Nocodazole disrupts microtubule polymerization. If Cdc50C is involved in processes that require intact microtubules, such as vesicle transport or cell division, nocodazole's action would indirectly lead to decreased functionality of Cdc50C by impairing those processes.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$321.00
$1040.00
5
(0)

CK 666 is an Arp2/3 complex inhibitor, which prevents actin nucleation and branching. If Cdc50C function is associated with actin-based structures, CK-666 would indirectly decrease its activity by destabilizing those structures.

Gö 6976

136194-77-9sc-221684
500 µg
$227.00
8
(1)

Gö 6976 is a protein kinase C (PKC) inhibitor. PKC is involved in various signaling pathways, and if Cdc50C is regulated by PKC-mediated phosphorylation, Gö6976 could indirectly decrease the functional activity of Cdc50C.

Latrunculin B

76343-94-7sc-203318
1 mg
$240.00
29
(1)

Latrunculin B binds to actin monomers and prevents their polymerization. If Cdc50C is involved in processes that depend on actin filament formation, the presence of Latrunculin B would indirectly lead to a decrease in Cdc50C activity.

ZCL278

587841-73-4sc-507369
10 mg
$115.00
(0)

ZCL278 is an inhibitor of Cdc42-mediated signaling. This compound would indirectly diminish Cdc50C activity if it is involved in Cdc42-dependent pathways, especially those linked to vesicle formation and trafficking.

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$184.00
$305.00
59
(1)

Jasplakinolide stabilizes actin filaments and prevents their disassembly. As Cdc50C may function in concert with dynamic actin structures, stabilization by Jasplakinolide could paradoxically decrease Cdc50C activity by impeding actin turnover required for its function.