Cdc42 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Toxin A from Clostridium difficile | sc-222361 sc-222361A | 2 µg 100 µg | $196.00 $787.00 | |||
Toxin A from Clostridium difficile acts as a potent disruptor of cellular signaling by targeting the Rho family of GTPases, particularly Cdc42. It catalyzes the ADP-ribosylation of Cdc42, leading to altered cytoskeletal dynamics and impaired cell adhesion. This modification triggers a cascade of downstream effects, including disruption of tight junctions and modulation of inflammatory responses, ultimately affecting cellular morphology and function. The toxin's specificity for Cdc42 highlights its role in manipulating host cell pathways. | ||||||
CASIN | 425399-05-9 | sc-397016 | 10 mg | $460.00 | 1 | |
CASIN inhibits Cdc42 activity by targeting its GTPase activity, possibly affecting its expression. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
ML141 is a potent inhibitor of Cdc42, preventing its activation and potentially leading to decreased expression. | ||||||
SecinH3 | 853625-60-2 | sc-203260 | 5 mg | $278.00 | 6 | |
SecinH3 inhibits Cdc42 by disrupting its interaction with guanine nucleotide exchange factors (GEFs). | ||||||
EHT 1864 | 754240-09-0 | sc-361175 sc-361175A | 10 mg 50 mg | $213.00 $889.00 | 12 | |
EHT 1864 is a Rac family small GTPase inhibitor, which includes Cdc42, and can down-regulate its expression. | ||||||
ITX 3 | 347323-96-0 | sc-295214 sc-295214A | 10 mg 50 mg | $145.00 $615.00 | ||
ITX3 inhibits the interaction of Cdc42 with its effector proteins, potentially reducing Cdc42 activity. | ||||||
Rhosin | 1173671-63-0 | sc-507401 | 25 mg | $555.00 | ||
Rhosin is a selective inhibitor of RhoA/Cdc42, potentially down-regulating Cdc42 expression. | ||||||