CD39L1 Activators
CD39L1 activators refers to a class of chemical compounds that have the unique capability to modulate the activity of the CD39L1 enzyme, also known as ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3). CD39L1 is a member of the ectonucleoside triphosphate diphosphohydrolase (ENTPD) family, primarily involved in the regulation of purinergic signaling pathways. Purinergic signaling, which encompasses the transmission of signals mediated by purine nucleotides like ATP and ADP, plays a pivotal role in various physiological processes, such as neurotransmission, immune responses, and inflammatory reactions. CD39L1 itself functions as an ectonucleotidase, actively participating in the hydrolysis of extracellular ATP and ADP, thus contributing to the fine-tuning of the purinergic signaling network.
CD39L1 activators, within this chemical class, are instrumental in modulating CD39L1's catalytic activity. These compounds may directly interact with the enzyme to enhance its hydrolytic function or indirectly influence its activity by altering the availability of its substrates, such as ATP and ADP. By stimulating CD39L1, these activators can have far-reaching consequences in the regulation of purinergic signaling. This class of chemicals is essential for researchers and scientists studying the intricate mechanisms of purinergic signaling and its involvement in various cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
As an endogenous nucleoside, adenosine directly activates adenosine receptors, contributing to the stimulation of purinergic signaling pathways, which may indirectly activate CD39L1. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin acts as an ionophore that triggers the release of intracellular ATP, potentially enhancing substrate availability for CD39L1 and indirectly activating purinergic signaling. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin is both a P2 receptor antagonist and an ectonucleotidase inhibitor. By blocking P2 receptors, it indirectly modulates purinergic signaling and activates changes in ATP and ADP levels, which can impact CD39L1. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
cAMP functions as a secondary messenger that directly activates purinergic signaling pathways, potentially activating CD39L1 indirectly. | ||||||
Guanosine | 118-00-3 | sc-218575 sc-218575A sc-218575B sc-218575C sc-218575D | 5 g 25 g 250 g 1 kg 5 kg | $40.00 $50.00 $84.00 $250.00 $1103.00 | ||
Guanosine, as a purine nucleoside, can directly activate adenosine receptors and the purinergic signaling network, potentially activating CD39L1 indirectly. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram, as a selective phosphodiesterase 4 (PDE4) inhibitor, directly elevates intracellular cAMP levels, activating purinergic signaling pathways that may indirectly activate CD39L1. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a synthetic glucocorticoid, directly modulates immune responses and inflammation, which are linked to purinergic signaling, potentially activating CD39L1 indirectly. | ||||||