CD209d Activators
Cd209d, encoding the CD209d molecule, exhibits a diverse range of predicted functions, including identical protein binding, mannose binding, and virus receptor activities. This versatility suggests its crucial role in immune responses and viral interactions. Cd209d is implicated in various processes such as B cell adhesion, positive regulation of T cell proliferation, defense response to bacteria, endocytosis, and positive regulation of the viral life cycle. The predicted subcellular localization at the plasma membrane, specifically the external side, emphasizes its role in direct interactions with extracellular factors. Activation of Cd209d involves intricate cellular mechanisms and can be influenced by various chemical activators. Mannose and C-type lectin receptor agonists directly engage Cd209d, triggering specific binding activities and enhancing its function. Signaling pathways such as TLR3, TLR4, and SMAD are implicated in Cd209d activation, with compounds like Poly I:C, LPS, and TGF-β influencing these pathways, respectively. Additionally, interferon-gamma and zinc modulate Cd209d expression, showcasing the complex regulatory networks governing its activity. Ribavirin, affecting the viral life cycle, and statins, modulating cholesterol biosynthesis, indirectly influence Cd209d expression, adding another layer to its multifaceted activation.
In summary, Cd209d emerges as a key player in immune regulation, with its activation intricately tied to various signaling pathways and cellular processes. The diverse range of activators highlights its adaptability and responsiveness to different environmental cues, emphasizing its significance in orchestrating immune responses and interactions with viral pathogens. The intricate interplay of these activators provides a nuanced perspective on Cd209d's versatile involvement in immune processes and viral interactions, positioning it as a critical component of the immune system.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $103.00 $161.00 | 1 | |
Direct activator of Cd209d mannose binding. Binds to Cd209d, triggering mannose binding activity and enhancing its function. This chemical directly promotes Cd209d activity by facilitating mannose binding, a key aspect of its predicted function. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
Indirect activator of Cd209d via VDR signaling. Calcitriol binds to VDR, promoting Cd209d expression. This compound influences immune responses and positively modulates Cd209d activity through the vitamin D pathway. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
Activates Cd209d through TLR4 signaling. Agonists like LPS bind to TLR4, initiating downstream signaling that enhances Cd209d expression. This compound directly promotes Cd209d activity by triggering TLR4-mediated signaling and subsequent upregulation. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
Activates Cd209d through TLR3 signaling. Poly I:C engages TLR3, initiating downstream signaling that enhances Cd209d expression. This compound directly promotes Cd209d activity by triggering TLR3-mediated signaling and subsequent upregulation. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Upregulates Cd209d through zinc-dependent transcription factors. Zinc positively influences Cd209d gene expression, promoting its function. This compound indirectly activates Cd209d by modulating transcription factors dependent on zinc availability. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B sc-214454C | 10 g 25 g 100 g 1 kg | $43.00 $62.00 $141.00 $430.00 | ||
Indirect activator of Cd209d via antioxidant pathways. α-Tocopherol positively modulates Cd209d activity by influencing antioxidant pathways. This compound indirectly activates Cd209d by enhancing cellular antioxidant responses and positively influencing gene expression. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
Upregulates Cd209d by influencing the viral life cycle. Ribavirin modulates viral replication, positively affecting Cd209d expression. This compound indirectly activates Cd209d by influencing the viral life cycle and subsequently enhancing gene expression. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $31.00 $89.00 $135.00 $443.00 | 13 | |
Indirect activator of Cd209d via HMG-CoA reductase inhibition. Statins modulate the mevalonate pathway, indirectly influencing Cd209d expression. These compounds indirectly activate Cd209d by modulating cholesterol biosynthesis and affecting gene expression. | ||||||