CCDC78 Inhibitors
Compounds like ML-7 and Y-27632 target kinases involved in cytoskeletal dynamics and could thus interfere with any roles CCDC78 plays in cellular organization. PD98059 and U0126 specifically target the MEK/ERK pathway, a signaling cascade that can regulate a variety of cellular functions including those associated with CCDC78.
Further along these lines, SB203580, SP600125, and Staurosporine have the capacity to modulate stress-activated pathways and broad signaling cascades, which can indirectly impact CCDC78's activity. PI3K, a key regulator of intracellular signaling, can be inhibited by compounds like LY294002 and Wortmannin, thereby potentially altering the cellular context within which CCDC78 operates. Rapamycin, by inhibiting mTOR, can affect protein synthesis and cellular growth, pathways where CCDC78 might have a role. Additionally, Blebbistatin and Gö6983 offer more targeted approaches, the former by inhibiting myosin II ATPase and the latter by inhibiting protein kinase C. Both enzymes are integral to cell contractility and signaling, with possible connections to CCDC78's function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibitor of myosin light chain kinase, which could affect cytoskeletal dynamics related to CCDC78's presumed role in cellular structure and organization. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibitor of Rho-associated protein kinase (ROCK) that can alter cytoskeletal organization, potentially affecting CCDC78's cellular function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can alter downstream ERK signaling, potentially influencing the signaling pathways that regulate CCDC78. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAP kinase inhibitor that can modulate stress response pathways, potentially affecting CCDC78's role in these pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can alter a range of cellular processes including those related to CCDC78's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor that can affect cellular growth and proliferation pathways, potentially influencing CCDC78's function. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can affect multiple signaling pathways, potentially altering CCDC78's activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Selective inhibitor of MEK1/2, which can influence ERK signaling pathways related to CCDC78. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibitor of c-Jun N-terminal kinase (JNK), which could affect signaling pathways involving CCDC78. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor that can influence a broad range of cellular processes, potentially affecting CCDC78's function. | ||||||