Date published: 2026-2-14

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CCDC63 Inhibitors

CCDC63 Inhibitors encompass a diverse range of compounds that can indirectly influence its functional activity through their effects on various cellular processes and signaling pathways. For example, Brefeldin A and Monensin are known to disrupt the function and maintenance of the Golgi apparatus, which could lead to the mislocalization or improper post-translational modification of CCDC63, thereby impairing its function. Similarly, microtubule-targeting agents such as Paclitaxel and Nocodazole, which are known to arrest cell cycle progression, could indirectly inhibit CCDC63 function if it is contingent upon cell cycle cues or microtubule dynamics. Additionally, the actions of CDK inhibitors like Purvalanol A, which prevent cell cycle progression, can indirectly lead to the inhibition of CCDC63 if its activity is regulated through cell cycle-dependent signaling pathways. Inhibitors of key mitotic kinases, such as MLN8237, ZM447439, and BI 2536, demonstrate the potential to inhibit CCDC63 by disrupting processes like chromosome alignment, spindle assembly, and mitotic exit, which could be essential for the proper function of CCDC63.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

A fungal metabolite that disrupts the function of the Golgi apparatus. By inhibiting protein transport from the ER to the Golgi, Brefeldin A can lead to a decrease in the functional activity of CCDC63 if its proper localization is critical for function.

Monensin A

17090-79-8sc-362032
sc-362032A
5 mg
25 mg
$155.00
$525.00
(1)

An ionophore that alters the pH and ion gradients in cellular compartments, particularly the Golgi. Monensin's disruption of Golgi function can indirectly inhibit CCDC63 if it relies on Golgi-mediated post-translational modifications for activity.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

A microtubule-stabilizing agent that can disrupt cellular division. If CCDC63 is involved in cell cycle progression, paclitaxel's stabilization of microtubules can indirectly inhibit the protein's function by arresting cells in specific phases.

Nocodazole

31430-18-9sc-3518B
sc-3518
sc-3518C
sc-3518A
5 mg
10 mg
25 mg
50 mg
$59.00
$85.00
$143.00
$247.00
38
(2)

A microtubule-depolymerizing agent that can arrest cells in the M-phase. If CCDC63 function is associated with cell cycle regulation, nocodazole can lead to functional inhibition of CCDC63 by halting cell cycle progression.

Purvalanol A

212844-53-6sc-224244
sc-224244A
1 mg
5 mg
$72.00
$297.00
4
(2)

These inhibitors prevent the activation of CDKs. If CCDC63 activity is regulated by cell cycle checkpoints, CDK inhibitors can indirectly inhibit CCDC63 by preventing cell cycle progression.

MLN8237

1028486-01-2sc-394162
5 mg
$220.00
(0)

An Aurora kinase A inhibitor that disrupts chromosome alignment and segregation. If CCDC63 is involved in mitotic processes, MLN8237 can inhibit its function by disturbing proper chromosome segregation during mitosis.

ZM-447439

331771-20-1sc-200696
sc-200696A
1 mg
10 mg
$153.00
$356.00
15
(1)

An Aurora kinase inhibitor that affects spindle checkpoint function. If CCDC63 has a role in spindle assembly or maintenance, ZM447439 can inhibit its function by disrupting these processes.

BI 2536

755038-02-9sc-364431
sc-364431A
5 mg
50 mg
$151.00
$525.00
8
(1)

A Plk1 inhibitor that can arrest cells in mitosis. If CCDC63's functional activity is linked to mitotic progression, BI 2536 can lead to its inhibition by arresting cells and preventing mitotic exit.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$78.00
$260.00
18
(1)

An inhibitor of ribonucleotide reductase that leads to DNA replication stress. If CCDC63 is involved in DNA damage response or repair, hydroxyurea can indirectly inhibit its function by inducing replication stress and activating damage checkpoints.

(S)-(−)-Blebbistatin

856925-71-8sc-204253
sc-204253A
sc-204253B
sc-204253C
1 mg
5 mg
10 mg
25 mg
$72.00
$265.00
$495.00
$968.00
(2)

An inhibitor of non-muscle myosin II ATPase activity. If CCDC63 is involved in cellular motility or cytoskeletal rearrangements, blebbistatin's inhibition of myosin II can lead to functional inhibition of CCDC63.