CCDC48 Activators
CCDC48 activators belong to a specialized group of compounds that target and enhance the function of the CCDC48 protein, a member of the coiled-coil domain-containing (CCDC) protein family. These proteins are characterized by their structural motif, the coiled-coil domain, which facilitates a wide array of protein-protein interactions and is involved in various cellular processes, including but not limited to, vesicle trafficking, cytoskeletal organization, and the assembly of protein complexes. The exact biological function of CCDC48 remains an area ripe for exploration, with activators of this protein serving as valuable tools for probing its role within the cellular milieu. By increasing the activity or expression levels of CCDC48, these activators can provide insights into the protein's contribution to cellular architecture and dynamics, potentially uncovering new aspects of cellular organization and function that are mediated by the coiled-coil domain.
The development and study of CCDC48 activators necessitate a multidisciplinary approach, encompassing synthetic chemistry for the creation of the activators, molecular biology to elucidate the interaction between the activators and the CCDC48 protein, and cellular biology to observe the resultant changes in cell behavior. These activators are designed based on an understanding of the CCDC48 structure and its interaction sites, aiming to bind to the protein in a manner that promotes its activity or stabilizes its structure. Investigating the effects of CCDC48 activation involves a range of techniques, from in vitro assays to determine binding affinity and specificity, to in vivo studies assessing the impact on cellular processes such as organelle assembly, protein trafficking, or cell motility. Through such comprehensive analyses, the role of CCDC48 in maintaining cellular integrity and facilitating intermolecular interactions can be better understood, shedding light on the intricate network of protein interactions that underpin cellular function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 regulates gene expression by binding to the vitamin D receptor, potentially influencing expression of various genes. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $46.00 $92.00 $117.00 | 3 | |
Salicylic acid can affect the activation of various transcription factors and signaling pathways, potentially altering gene expression. | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $25.00 $80.00 $136.00 | 8 | |
Sodium salicylate modulates the NF-κB pathway which is involved in the expression of many genes. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
Arsenic trioxide can induce stress responses and affect gene expression through various signaling mechanisms. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR activates AMPK, a cellular energy sensor that can regulate gene expression by influencing transcription factors. | ||||||
Sodium phenylbutyrate | 1716-12-7 | sc-200652 sc-200652A sc-200652B sc-200652C sc-200652D | 1 g 10 g 100 g 1 kg 10 kg | $75.00 $163.00 $622.00 $4906.00 $32140.00 | 43 | |
As an HDAC inhibitor, sodium phenylbutyrate affects chromatin structure and gene expression. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine has been implicated in epigenetic regulation and may influence gene expression through histone acetylation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling, which can lead to changes in the expression of genes involved in cell growth and metabolism. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin activates AMPK and may have wide-ranging effects on gene expression related to energy metabolism. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone activates PPARγ, potentially inducing expression of genes involved in lipid metabolism and insulin sensitivity. | ||||||