CCDC41 Inhibitors
CCDC41 Inhibitors currently refers to a collection of compounds that, due to the lack of direct inhibitors for CCDC41, encompass a range of molecules that target associated or related cellular pathways. In particular, these inhibitors modulate signaling cascades like the PI3K, MEK/ERK, JNK, and mTOR pathways. For example, inhibitors like Wortmannin and LY294002 target the PI3K pathway, influencing proteins that either function within or have interactions related to this cascade. Similarly, PD98059 and U0126, which target MEK, can indirectly affect proteins associated with the MEK/ERK pathway, another arena of CCDC41 interaction.
Another avenue of indirect modulation comes from proteasome inhibitors like Bortezomib, which can influence protein stability and degradation rates across the cell. By changing the proteomic landscape, the functional interactions and stability of proteins like CCDC41 can be altered. Additionally, molecules such as Nutlin-3, which modulate the MDM2-p53 interaction, showcase the strategy of targeting protein-protein interactions that might be upstream or associated with CCDC41's role. Given the lack of direct inhibitors, the understanding and specificity of molecules impacting CCDC41 activity necessitates further research to elucidate its exact role and druggable targets.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin can inhibit PI3K, a kinase involved in various cellular pathways. If CCDC41 interacts within these pathways, its function can be indirectly affected. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Another PI3K inhibitor. By inhibiting PI3K activity, it can influence proteins that are part of or interact with this pathway. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad kinase inhibitor that targets multiple kinases. Its broad activity can impact various pathways, possibly affecting CCDC41 indirectly. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
This compound inhibits MEK, a kinase upstream of ERK. If CCDC41 functions within or interacts with the MEK/ERK pathway, its activity can be influenced. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK. By modulating the JNK pathway, proteins that might be linked or have downstream effects related to this pathway can be impacted. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor. By targeting p38, this compound can influence proteins that are associated with the p38 pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor. mTOR regulates various cellular processes, and inhibiting it can affect proteins that function within its associated pathways. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor. By affecting protein degradation, it can influence the stability and function of various proteins, including potentially CCDC41. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
An Aurora kinase inhibitor. If CCDC41 interacts with or is involved in processes modulated by Aurora kinases, its function can be indirectly impacted. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $62.00 $225.00 $779.00 | 24 | |
MDM2-p53 interaction inhibitor. By modulating p53 activity, it can affect proteins that are downstream or associated with the p53 pathway. | ||||||