CCDC158 Inhibitors

Chemicals that can be classified as CCDC158 Inhibitors are not direct inhibitors in the traditional sense but rather agents that can affect the cellular processes and pathways where CCDC158 might play a role. These compounds include those that target the cytoskeleton, such as colchicine and paclitaxel, which can disrupt microtubule dynamics, potentially influencing CCDC158's involvement in cell structure and division. Similarly, cytochalasin D, nocodazole, and latrunculin A can alter actin filaments, which may affect CCDC158's role in maintaining cellular architecture.

The second group of compounds includes those that affect cell contractility and motility, such as ML-7, blebbistatin, and Y-27632, which inhibit various motors and kinases that regulate the cytoskeleton and cell motility. These inhibitors can influence the structural context within which CCDC158 operates. Withaferin A and jasplakinolide, by altering the integrity of cytoskeletal elements, can also impact the functional capacity of CCDC158. Ciliobrevin D and dynasore offer examples of compounds that can influence more specific cellular structures and processes, such as ciliogenesis and vesicular trafficking, respectively, which could involve CCDC158 either directly or indirectly.