CCDC138 Inhibitors
Staurosporine and Roscovitine, target a wide range of kinases, potentially impacting numerous signaling cascades that might intersect with CCDC138's function. Compounds like Brefeldin A and Thapsigargin disrupt normal cellular organelle functions, which could alter the environment or processing of proteins like CCDC138. Proteasome inhibitors, such as MG132, and calpain inhibitors, like ALLN, prevent the degradation of proteins, which could indirectly lead to an increase in CCDC138 levels or the stabilization of its structure.
Microtubule-targeting agents, namely Taxol and Nocodazole, affect cell division, and if CCDC138 is involved in this process, these compounds could influence its function. Compounds that modulate the cell cycle, such as Roscovitine and ZM447439, would also be relevant if CCDC138 plays a role in cell cycle regulation. Lithium Chloride and 5-Azacytidine modify signaling and gene expression, respectively, and could indirectly affect the expression or activity of CCDC138. Y-27632 affects cell shape and motility, which are processes that may involve CCDC138 if it functions in cytoskeletal organization.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can affect multiple signaling pathways, potentially altering the function or regulation of CCDC138. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
An inhibitor of ADP-ribosylation factor (ARF), which disrupts Golgi apparatus function, possibly affecting proteins related to CCDC138. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that can increase cellular protein levels by preventing degradation, potentially impacting CCDC138 levels. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules and can disrupt cell division, potentially influencing the mitotic roles of CCDC138. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule-depolymerizing agent that can arrest cells in mitosis, potentially affecting CCDC138-related processes. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
An inhibitor of glycogen synthase kinase 3 (GSK-3), which may impact Wnt signaling, potentially influencing pathways involving CCDC138. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
A cyclin-dependent kinase (CDK) inhibitor that can arrest cell cycle progression, potentially affecting CCDC138's role if related to cell cycle control. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can cause epigenetic changes, potentially affecting the expression of genes like CCDC138. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A Rho-associated protein kinase (ROCK) inhibitor, potentially affecting cell shape and motility processes linked with CCDC138. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
An Aurora kinase inhibitor that disrupts chromosome alignment and segregation, potentially influencing CCDC138's function if related to mitosis. | ||||||