CCDC136 Inhibitors
CCDC136, a protein intricately involved in acrosome assembly and single fertilization processes, boasts a unique role as an integral component of the cellular membrane. The exploration of chemical inhibitors provides a comprehensive view of avenues targeting this critical player in reproductive biology. Nocodazole stands out as an indirect inhibitor disrupting CCDC136's function. By altering microtubule dynamics, it impacts acrosome assembly and single fertilization processes. This interference influences the integral membrane component function of CCDC136 within the acrosomal membrane, shedding light on potential regulatory mechanisms. Colchicine, Vinblastine, and Paclitaxel further emphasize the significance of microtubule modulation. These indirect inhibitors either disrupt microtubule polymerization or stabilize microtubules, collectively influencing CCDC136 and its role in acrosome assembly. Their impact on the integral membrane component function provides valuable insights into the intricacies of CCDC136-related cellular events.
Griseofulvin, Thiabendazole, and Vinorelbine showcase additional indirect inhibitors affecting CCDC136 through microtubule interference. These compounds underscore the connection between microtubule dynamics and CCDC136's involvement in acrosomal membrane activities. Podophyllotoxin, Albendazole, and Colcemid add to the repertoire of indirect inhibitors, emphasizing their impact on microtubule dynamics and, consequently, CCDC136. These compounds influence the integral membrane component function, providing a nuanced understanding of CCDC136's regulation in cellular processes. Combretastatin A-4 and Vincristine round off the list of indirect inhibitors, further highlighting the interplay between microtubules and CCDC136. Their effects on acrosome assembly and single fertilization processes underscore the intricate web of cellular events modulated by CCDC136. In conclusion, the diverse range of CCDC136 inhibitors, intricately connected to microtubule dynamics, illuminates the multifaceted nature of this protein's role in cellular processes.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Indirect inhibitor of CCDC136, disrupting microtubule dynamics and affecting acrosome assembly. Alters the intracellular milieu, potentially influencing the integral membrane component function of CCDC136 in acrosomal membrane activities and single fertilization processes. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Indirect inhibitor impacting CCDC136 by interfering with microtubule polymerization. Modulates acrosome assembly and single fertilization processes by disrupting the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Indirect inhibitor targeting CCDC136 through microtubule depolymerization. Alters acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Indirect inhibitor affecting CCDC136 by stabilizing microtubules. Modulates acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $83.00 $216.00 $586.00 | 4 | |
Indirect inhibitor of CCDC136, disrupting microtubule dynamics. Alters acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $31.00 $82.00 $179.00 $306.00 $561.00 | 5 | |
Indirect inhibitor targeting CCDC136 through microtubule interference. Modulates acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Vinorelbine base | 71486-22-1 | sc-205885 sc-205885A sc-205885B sc-205885C sc-205885D | 1 mg 5 mg 25 mg 100 mg 1 g | $28.00 $79.00 $255.00 $775.00 $1938.00 | ||
Indirect inhibitor impacting CCDC136 through microtubule disruption. Alters acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $82.00 | 1 | |
Indirect inhibitor of CCDC136, disrupting microtubule dynamics. Modulates acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Albendazole | 54965-21-8 | sc-210771 | 100 mg | $209.00 | 1 | |
Indirect inhibitor targeting CCDC136 through microtubule interference. Alters acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||
Colcemid | 477-30-5 | sc-202550A sc-202550 sc-202550B sc-202550C sc-202550D sc-202550E | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg | $67.00 $159.00 $312.00 $928.00 $1856.00 $6706.00 | 7 | |
Indirect inhibitor impacting CCDC136 through microtubule depolymerization. Modulates acrosome assembly and single fertilization processes by influencing the integral membrane component function of CCDC136 in acrosomal membrane. | ||||||