CCDC117, or Coiled-Coil Domain Containing 117, is a human protein encoded by the gene CCDC117. The function of CCDC117 is not extensively characterized, but as with other proteins that possess coiled-coil domains, it is likely to be involved in processes that require the formation of stable, oligomeric protein complexes.The coiled-coil motif is a structural motif that is prevalent in proteins that oligomerize, facilitating interactions between proteins. Such interactions are fundamental to the constitution of the cytoskeleton, vesicle transport, cell division, and signal transduction processes. Given this, CCDC117 may play a role in one or more of these cellular activities, possibly contributing to the structural integrity of cells or to the regulation of cellular division and signaling pathways.
Proteins with coiled-coil domains are often implicated in mediating molecular assemblies that are critical for the intracellular organization and are involved in various dynamic processes such as mitosis and intracellular trafficking.The expression pattern of CCDC117 might provide clues to its function. If the protein is ubiquitously expressed, it may be involved in fundamental cellular processes. Alternatively, tissue-specific expression could indicate specialized roles in certain cell types or organs.Mutations or alterations in the expression of the CCDC117 gene could potentially be linked to human diseases, especially those affecting cellular organization, division, or signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin, an mTOR inhibitor, might indirectly affect CCDC117 by modulating cellular growth and autophagy processes, which could influence proteins involved in these pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
As a PI3K inhibitor, LY294002 can influence various signaling pathways, potentially altering the expression or function of proteins like CCDC117 involved in cellular processes regulated by PI3K. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
By inhibiting p38 MAPK, SB203580 could indirectly influence CCDC117 function, as p38 MAPK is a key player in inflammatory responses and stress-induced cellular pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
As an inhibitor of PI3K, Wortmannin may alter CCDC117-related pathways by affecting cellular processes like growth, survival, and metabolism. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059, an inhibitor of MEK, may indirectly modulate CCDC117 activity by influencing the MAPK/ERK pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
As a JNK inhibitor, SP600125 might affect CCDC117 indirectly by modulating cellular stress responses and apoptosis pathways. | ||||||
LY3214996 | 1951483-29-6 | sc-507299 | 5 mg | $260.00 | ||
This ERK1/2 inhibitor potentially impacts CCDC117 indirectly by modulating signaling pathways involved in cell proliferation and differentiation. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $56.00 $169.00 | 8 | |
As an mTOR inhibitor like Rapamycin, Torin 1 can indirectly affect the function or expression of CCDC117 by altering cellular growth and autophagy pathways. | ||||||
BIX 02189 | 1094614-85-3 | sc-364436 sc-364436A | 5 mg 10 mg | $220.00 $378.00 | 5 | |
As a MEK5 inhibitor, BIX 02189 might indirectly influence CCDC117 through pathways involving the ERK5/MAPK7 cascade. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $28.00 $80.00 $412.00 $1860.00 $2962.00 | 5 | |
Selumetinib, a MEK inhibitor, could indirectly affect CCDC117 by modulating the MAPK/ERK pathway, impacting cell growth and differentiation. | ||||||