Date published: 2025-10-25

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CC2D2B Inhibitors

CC2D2B inhibitors represent a specialized class of chemical agents designed to selectively impede the activity of the CC2D2B protein. This protein, encoded by the CC2D2B gene, is implicated in various intracellular signaling cascades and physiological processes. The inhibitors targeting CC2D2B are structured to interfere with the protein's ability to engage in its typical cellular functions, which may include interactions with other proteins, participation in signaling complexes, or regulation of gene expression. While the precise mechanisms of action may vary among different members of the CC2D2B inhibitor class, the unifying feature is their capacity to bind to the CC2D2B protein in a manner that disrupts its normal activity. This binding can occur at the active site, allosteric sites, or at interfaces where CC2D2B would typically interact with other molecular entities. The development and characterization of CC2D2B inhibitors hinge on a thorough understanding of the protein's structure-function relationship. The design of these molecules often involves sophisticated computational models to predict how they might interact with the three-dimensional conformation of CC2D2B. By targeting specific domains within the protein that are critical for its function, CC2D2B inhibitors can effectively reduce the biological activity of CC2D2B. The specificity of these inhibitors is crucial, as off-target effects can lead to unintended consequences within the cell. Therefore, the chemical scaffolds used in CC2D2B inhibitors are typically refined through iterative cycles of design, synthesis, and biological testing to enhance their selectivity and inhibitory potency. The result is a class of compounds that can precisely modulate the activity of CC2D2B within the complex network of cellular pathways in which it operates, providing a tool for dissecting the protein's role in cellular physiology and for investigating the biochemical pathways it influences.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Staurosporine is a potent inhibitor of protein kinases, which can indirectly lead to the inhibition of CC2D2B if CC2D2B's function is modulated by phosphorylation. By inhibiting the kinase activity, staurosporine would prevent the phosphorylation of CC2D2B, potentially reducing its activity if phosphorylation is a requirement for its function.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a phosphoinositide 3-kinases (PI3K) inhibitor. If CC2D2B operates downstream of PI3K signaling, inhibition of PI3K would result in reduced activation of pathways that may be necessary for CC2D2B activity, thus leading to its functional inhibition.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin is an mTOR inhibitor. If CC2D2B is involved in pathways regulated by mTOR, such as cell growth and proliferation, rapamycin would lead to a decrease in CC2D2B's function by inhibiting these pathways, assuming CC2D2B is a positive regulator within these pathways.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 is a MEK inhibitor, which blocks the MAPK/ERK pathway. If CC2D2B functions downstream of the MAPK/ERK pathway or is regulated by it, then inhibition of MEK would lead to decreased CC2D2B activity by preventing its activation through this pathway.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 is a p38 MAPK inhibitor. It would inhibit the function of CC2D2B if the protein's activity is modulated via the p38 MAPK signaling pathway. By blocking p38 MAPK, SB203580 would indirectly prevent the activation or proper functioning of CC2D2B if it is a component of this signaling cascade.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$63.00
$241.00
136
(2)

U0126 is another MEK inhibitor, which would lead to the inhibition of CC2D2B activity by blocking MEK1/2, assuming that CC2D2B is regulated by the MEK/ERK pathway. This would result in the downregulation of the ERK pathway, thereby inhibiting the activity of CC2D2B if it is part of this signaling cascade.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK). If CC2D2B's activity is associated with the JNK signaling pathway, inhibition of JNK by SP600125 would lead to a decrease in CC2D2B activity by preventing its activation within this signaling pathway.

WZ4003

1214265-58-3sc-473979
5 mg
$300.00
(0)

WZ4003 is a selective inhibitor of NUAK kinases. If CC2D2B is regulated through NUAK signaling pathways, inhibition by WZ4003 would decrease CC2D2B activity by disrupting the associated signaling that would typically result in CC2D2B activation.

BIX 02189

1094614-85-3sc-364436
sc-364436A
5 mg
10 mg
$220.00
$378.00
5
(1)

BIX 02189 is an inhibitor of MEK5, which is part of the ERK5 pathway. If CC2D2B is regulated by ERK5 signaling, inhibition by BIX 02189 would lead to decreased activity of CC2D2B by preventing its activation or the propagation of signals within this pathway.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Y-27632 is a Rho-associated protein kinase (ROCK) inhibitor. If CC2D2B functions downstream of ROCK signaling, Y-27632 would inhibit CC2D2B activity by blocking ROCK, which could be necessary for the proper functioning or activation of CC2D2B.