caveolin-2 Inhibitors
The chemical class of Caveolin-2 Inhibitors includes a range of compounds that can potentially suppress or modulate the expression and activity of Caveolin-2, primarily through effects on cholesterol metabolism, kinase activity, and cellular signaling. Cholesterol-lowering statins like Atorvastatin and Lovastatin, cholesterol-extracting compounds like Methyl-β-cyclodextrin and Filipin, and kinase inhibitors such as Genistein, Roscovitine, Dasatinib, and Gefitinib are included due to their roles in altering membrane dynamics and signaling pathways.
Nystatin, which alters membrane cholesterol, and 2-Bromopalmitate, a palmitoylation inhibitor, could impact Caveolin-2 by influencing post-translational modifications and membrane structure. Sodium Nitroprusside, as a nitric oxide donor, and Everolimus, an mTOR inhibitor, are considered for their potential to modulate various cellular processes and signaling pathways related to Caveolin-2.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $257.00 $505.00 | 9 | |
A statin that lowers cholesterol, potentially disrupting caveolae formation and affecting Caveolin-2. | ||||||
Methyl-β-cyclodextrin | 128446-36-6 | sc-215379A sc-215379 sc-215379C sc-215379B | 100 mg 1 g 10 g 5 g | $20.00 $48.00 $160.00 $82.00 | 19 | |
Extracts cholesterol from cell membranes, potentially disrupting caveolae formation and Caveolin-2 function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor, could affect signaling pathways associated with Caveolin-2. | ||||||
Filipin III | 480-49-9 | sc-205323 sc-205323A | 500 µg 1 mg | $118.00 $148.00 | 26 | |
Binds to cholesterol, potentially disrupting caveolae structures and affecting Caveolin-2. | ||||||
Nystatin | 1400-61-9 | sc-212431 sc-212431A sc-212431B sc-212431C | 5 MU 25 MU 250 MU 5000 MU | $51.00 $129.00 $251.00 $3570.00 | 7 | |
Alters membrane cholesterol and could impact Caveolin-2 associated structures. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
A cyclin-dependent kinase inhibitor that could potentially affect signaling pathways involving Caveolin-2. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Can release nitric oxide and modulate various signaling pathways, potentially influencing Caveolin-2. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
A Src kinase inhibitor, could indirectly affect Caveolin-2 function. | ||||||
2-Bromohexadecanoic acid | 18263-25-7 | sc-251714 sc-251714A | 10 g 50 g | $53.00 $201.00 | 4 | |
Inhibits protein palmitoylation, a critical post-translational modification for Caveolin-2. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $29.00 $90.00 $339.00 | 12 | |
Another specific statin that lowers cholesterol, potentially affecting Caveolin-2 by altering cell membrane dynamics. | ||||||